Center for Oral Biology


JessicaCourses are aimed at ensuring that students receive the fundamental information essential in their chosen discipline. The courses listed below, in combination with the required research rotations and seminars, comprise the core curricula for the M.S. program in Dental Science. The curriculum for the various Ph.D. programs are defined by those programs but will include a number of these.


Core Curricula

ORB 493. Oral Microbiology The major groups of microorganisms causing oral disease are reviewed with emphasis on basic biology, genetics, physiology, and pathogenic mechanisms.

ORB 501-504. Dental Research Seminar The purpose of this series is to provide experience to participants in preparing, organizing, and presenting material to a critical audience. The fall semesters are devoted to a systematic review of recent significant research developments in one of the basic sciences fundamental to Oral Biology. In the spring semesters the students report on original research. Required of all graduate students in oral biology and open to other graduate students and dentists.

ORB 579. Saliva and Salivary Glands This course gives students an understanding of the fundamental biology of the salivary glands. The regulation of salivary gland physiology is discussed, as is the structure/function relationship of salivary proteins and lipids. The molecular basis of salivary gland gene expression is explored. The etiology, pathogenesis, and consequences of salivary gland diseases are also discussed.

ORB 580. Fundamentals of Dental Caries This course presents the latest developments in many aspects of dental caries, from the most fundamental basic science to clinical applications.

IND 501. Ethics in Research Ethics and Professional Integrity aims to bring to light some of the salient issues related to ethics and responsible conduct in clinical and basic science biomedical research arenas. The course meets weekly for 90 minutes for 10 weeks. A broad range of topics is covered, including the University of Rochester policy and procedures regarding human and animal experimentation, intellectual property, as well as scientific misconduct. The course emphasizes experiential learning in small group format, and case studies are used to facilitate active discussion and interaction. In addition, the course features a series of "survival skills" presentations aimed at helping students advance in their career paths with integrity and with the highest of ethical standards.

Other courses administered by the Center of Oral Biology which may be chosen as part of the program of study

ORB 414. Mechanisms of Microbial Pathogenesis The molecular mechanisms by which bacteria cause disease are examined. The emphasis is on understanding how bacteria colonize the host, evade host immune defenses, and cause damage to the host, as well as understanding the regulation of synthesis, structure, function, and mode of action of bacterial toxins.

ORB 556. Biology of the Periodontium Stressing the biological behavior of the periodontium, the course reviews the fundamentals as well as the latest developments in periodontal research. Topics covered are the development, morphology, and physiology of the periodontal tissues, the epidemiology, etiology and histopathology of periodontal diseases, plus current concepts regarding mechanisms of periodontal tissue destruction and repair.

ORB 558. Craniofacial Growth and Development This series covers the prenatal embryogenesis and postnatal growth and development of the craniofacial complex. Mechanisms of growth control, the development of occlusion, and methods of study and timing are presented. Clinical implications for normal and abnormal facial development are discussed.

ORB 563. Pharmacology and Therapeutics Pharmacotherapeutics of drugs most often used in dentistry are reviewed with emphasis on critical analysis of the related literature and current directions in pharmacological research.

ORB 570. Introduction to Dental Epidemiology and Research Design Students are introduced to the fundamentals of epidemiology. Emphasis is placed on the natural history of common dental diseases.

ORB 593. Complex Carbohydrates The synthesis, structure, and function of complex carbohydrates is considered with emphasis on recognition phenomena.

Some courses administered by other centers and departments that are frequently chosen by students

IND 408. Biochemistry

MBI 473. Immunology

STT 212. Applied Statistics for the Biological and Physical Sciences

LAM 402. Laboratory Animal Experiments

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