Muscular Dystrophy Cooperative Research Center

Scientific Cores

One Scientific Core is an Imaging Core. It provides specialized muscle histochemical and immunological techniques, fluorescent in situ hybridization, confocal microscopy, and electron microscopy. Projects 1 & 3 make extensive use of this Core.

The other Scientific Core is a Repository Core of resources for research on dominantly inherited muscular dystrophies. This Repository Core maintains: a) myoblast cell lines for DM1 & FSHD; b) transgenic model cell lines; c) plasmids; d) antibodies; e) autopsy tissue from DM1 patients; and, f) gene expression data on DM1 & FSHD patients. Projects 1, 2, & 3 interact with the Repository Core and this Core will interact with the other MDCRCs and serve as a national resource to other investigators.