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Image Captions (images courtesy of Kate Wright, graduate student fellow in the laboratory of Jay E. Reeder, Ph.D.):

Large image: Hematoxylin and eosin stained tissue culture of the mouse P19 embryonal carcinoma cell line induced to neuronal differentiation by retinoic acid. A gene that we are studying, DBCCR1, appears to be important in the process.

Top right: Three color fluorescence microscopy in which the cellular distribution of two proteins (red and green colors) can be visualized together with the DNA (blue color).

Bottom right: Fluorescence in situ hybridization. Three copies of chromosome 9 (green spots) can be seen in this nucleus. The DNA is stained with a fluorescent blue dye.