May 6, 2015
Professors Dalecki and Hocking Research Wins Best Paper Award at SPIE-DSS
The latest research by Professor Diane Dalecki (BME, RCBU) and Professor Denise C. Hocking (Pharmacology & Physiology, BME, RCBU) was recognized with the Best Paper Award at the Micro- and Nanotechnology Sensors, Systems, and Applications Conference of the SPIE Defense + Security Symposium held recently in Baltimore, Maryland. Their invited paper titled “Guiding Tissue Regeneration with Ultrasound In Vitro and In Vivo” detailed three biomedical ultrasound technologies under development in their laboratories to stimulate tissue formation and regeneration. Co-authors of the paper included Sally Child, Carol Raeman, and BME graduate students Eric Comeau and Laura Hobbs. One technology under development employs forces within an ultrasound standing wave field to provide a noninvasive approach to spatially pattern endothelial cells and thereby guide the development of complex microvessel networks. A second technology uses ultrasound to site-specifically control the microstructure of collagen fibers within engineered hydrogels to direct cell function. The third line of research focuses on developing ultrasound as a therapeutic approach to enhance tissue regeneration in chronic wounds. These ultrasound technologies offer new solutions to key challenges currently facing the fields of tissue engineering, biomaterials fabrication, and regenerative medicine.
The SPIE DSS 2015 Defense + Security Symposium consisted of 32 separate conferences spanning 5 days with over 1200 total presentations. Conferences focused on a wide range of topics of interest to defense and security, including imaging, sensing, photonics, materials, and biomedical applications. The Symposium is the leading meeting for scientists, researchers and engineers from industry, military, government agencies, and academia throughout the world. The Micro- and Nanotechnology Sensors, Systems, and Applications Conference is one of the two largest conferences within the entire Defense + Security Symposium, and Professors Hocking’s and Dalecki’s presentation was one of over 100 invited presentations in the conference.
April 29, 2015
BME Professor Steve McAleavey has been awarded a University of Rochester PumpPrimer II grant for his research project titled “Towards Diagnostic Ultrasonic Imaging of Tissue Non-Linearity: Strain Dependence of Shear Wave Velocity in Liver and Breast Tissue.”
This project is a first step towards a long-term goal of characterizing non-linear mechanical properties of tissues non-invasively and in vivo with ultrasound, with application to clinical disease monitoring as well as basic research.
April 29, 2015
Melinda Vander Horst presents at NCUR
Melinda Vander Horst (BME Class 2015) presented her recent research at the 29th Annual National Undergraduate Research Conference (NCUR) held at Eastern Washington University in April. NCUR is an interdisciplinary conference where undergraduate students representing universities from around the world present their research and creative works. Melinda presented her poster, titled
Development of a dual transducer system for ultrasound standing wave field-induced particle banding, with co-authors Eric Comeau (BME graduate student), Denise C. Hocking (Pharmacology & Physiology), and Diane Dalecki (BME). Melinda is a Xerox Undergraduate Research Fellow working with Professors Dalecki and Hocking on new ultrasound technologies for tissue engineering.
March 30, 2015
Diane Dalecki Elected Vice Chair AIUM Bioeffects Committee
Diane Dalecki (BME) has been elected Vice Chair of the Bioeffects Committee of the American Institute of Ultrasound in Medicine (AIUM). Professor Dalecki is a Fellow of the AIUM, and Director of the Rochester Center for Biomedical Ultrasound (RCBU). The Bioeffects Committee provides information and guidance to the AIUM on matters relating to the biological effects and safety of ultrasound. In addition to the 14 elected AIUM members, the committee includes select resource members from federal agencies and external organizations. Following completion of a 2-year term as Vice Chair, Professor Dalecki will become Chair of the Bioeffects Committee. Professor Dalecki served previously as Chair of the Bioeffects Committee from 2001-2003. The AIUM is a multidisciplinary association of more than 9000 physicians, scientists, engineers, and clinicians dedicated to advancing the safe and effective use of ultrasound in medicine.
March 30, 2015
Emma Grygotis Wins Outstanding Presentation Award
Emma Grygotis receiving her Outstanding Presentation Award at the 2015 Therapeutic Ultrasound Winter School. Shown (Left to right) are conference organizers Gail ter Haar and Vera Khokhlova, and Emma Grygotis.
Emma Grygotis was the recipient of an Outstanding Student Presentation Award at the 2015 Therapeutic Ultrasound Winter School held in Les Houches, France at the École de Physique des Houches. At this forum, held in the French Alps on March 8-13, 2015, a group of twenty professors and fifty students gathered from around the world to discuss a range of topics in the rapidly expanding field of therapeutic ultrasound. Emma presented an overview of her studies focused on developing ultrasound technologies to fabricate bioactive collagen hydrogels for wound repair.
Attendees of the 2015 Therapeutic Ultrasound Winter School in the French Alps in Les Houches, France.
Emma is a second year graduate student in Pharmacology and Physiology working with Professor Denise Hocking (Pharmacology and Physiology, BME) and Professor Diane Dalecki (BME) on a joint collaboration to develop ultrasound technologies for tissue engineering and regenerative medicine. Emma is currently a pre-doctoral fellow in the HHMI Med-into-Grad program, and also a student member of the Rochester Center for Biomedical Ultrasound (RCBU). Recent BME alumna Karla Mercado, Ph.D. was also a participant at the 2015 Therapeutic Ultrasound Winter School.
March 25, 2015
BME Senior Design Team Focuses on Ultrasound Project
BME seniors help real-life customers solve biomedical engineering problems through the two-semester Senior Design course taught by RCBU member Amy Lerner and Scott Seidman. In the 2014-2015 academic year, one team of BME seniors is embarking on a project to develop an ultrasound-based technique to detect dentinal cracks in teeth. The team will focus on detection of cracks in mandibular molars, as these are the teeth that exhibit cracks often. The senior design team consists of BME students Alexa Kuenstler, Jonathan Macoskey, Jacob Hyatt, Tek Gautum, and Jenny Won. Long-standing RCBU member Robert Lerner, MD who serves as the customer for this project brought the problem to the team. Diane Dalecki, Ph.D. is the senior design team supervisor for this project.
March 17, 2015
John Cormack visits RCBU
John Cormack returned to Rochester and presented a lecture for the RCBU titled
Propagation of plane nonlinear shear waves in soft solids.John is a 2014 UR alumnus and is currently a graduate student at UT Austin working with Professor Mark Hamilton in the Applied Physics Laboratory. John's presentation to RCBU members provided an analytical approach to modeling the nonlinear propagation of shear waves in soft biological materials. While at the UR, John conducted research with Professor Sheryl Gracewski (ME) and Professor Jong-Hoon Nam (ME, BME).
February 1, 2015
Remembering Ultrasound Pioneer Floyd Dunn
The biomedical ultrasound community sadly lost one of its important pioneers. Floyd Dunn passed away on January 24, 2015 at the age of 90. Floyd was a member of the Electrical and Computer Engineering Department at the University of Illinois at Urbana-Champaign for over 50 years. Following the death of Bill Fry in 1968, Floyd became director of the Department’s Bioacoustics Research Laboratory and made it a world leader in the field of biomedical ultrasound. Founding RCBU Director Ed Carstensen writes,
It is hard to believe today, but in the mid-1960s, research in this field had dwindled to the point that progress could be reported in biannual sessions at meetings of the Acoustical Society. Floyd and Wesley Nyborg organized those special sessions and we are uniquely indebted to them for keeping the field alive.
Floyd's body of scientific work provides foundation for our understanding of the propagation of ultrasound in tissues and the biological effects of ultrasound. He was a member of both the National Academy of Sciences and the National Academy of Engineering, and served as President of the Acoustical Society America. He was recognized with the highest awards from numerous scientific societies, including the IEEE Edison Award, the ASA Gold and Silver Medal Awards, and the AIUM Joseph P. Holmes Basic Science Pioneer Award. He served on many FDA, NIH, AIUM, and ASA committees, and was a member of Committee 66 of the National Council on Radiation Protection.
Floyd was a Charter Honorary Member of the RCBU and was a long-time friend and colleague for many of us. The RCBU and the wider biomedical ultrasound community will miss Floyd dearly.
January 13, 2015
New Study Probes Link Between HIV Drugs and Vascular Disease
RCBU Faculty member Marvin Doyley, Ph.D., is a part of a multidisciplinary team that was recently awarded a $3.8 million grant from the National Institutes of Health to better understand why individuals who receive anti-retroviral treatment for HIV are at greater risk for heart disease and stroke.
The study will use a new ultrasound technology developed by Professor Doyley's group for one of the key measurements in the study -- tracking the thickness and stiffness of the carotid artery. Read more about the project here.
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