Rochester Oral Biology Research Conference
June 26-28, 2008
Saliva and Salivary Gland Function
All seminars will take place in the Class of ’62 Auditorium of the Kornberg Medical Research Building, 601 Elmwood Ave.
Thursday June 26
| 1:00-2:30 |
Registration |
| 2:30-2:45 |
Opening Remarks/Housekeeping |
| 2:45-5:45 |
Session I: Salivary Gland Development and Maintenance Co-Chairs: Catherine Ovitt & Kelly Ten Hagen |
| 2:45-3:15 |
Monn Monn Myat (Cornell): Salivary gland morphogenesis in Drosophilia |
| 3:15-3:45 |
Kelly Ten Hagen (NIDCR):
The role of mucin-type protein glycosylation during development |
| 3:45-4:15 |
Mindy Larsen (SUNY-Albany): Cell-cell and cell-matrix interactions in salivary gland development |
| 4:15-4:30 |
Break |
| 4:40-5:10 |
Denise Faustman (Harvard Medical School): Reversal of Sjögren’s-like syndrome from NOD mice to humans? |
| 5:10-5:40 |
Catherine Ovitt (Univ Rochester): Postnatal salivary gland progenitor cells |
| 5:45-7:00 |
Dinner |
| 7:15-8:00 |
Keynote Speaker -
Lawrence A. Tabak Lectureship Bruce Baum (NIDCR): Gene therapy for radiation-induced salivary gland damage |
Friday June 27
| 8:00-8:45 |
Breakfast |
| 9:00 |
James Melvin (Univ Rochester): Recognition of Abstract Awards |
| 9:00-12:00 |
Session II: Cell Signaling in Epithelial Cells
Co-Chairs: David Yule & Indu Ambudkar |
| 9:00-9:30 |
James Sneyd (Auckland): Part I - A systems biology approach to signaling |
| 9:30-10:00 |
David Yule (Univ Rochester): IP3-Ca2+ signaling |
| 10:00-10:30 |
Trevor Shuttleworth (Univ Rochester): Ca2+ entry pathways |
| 10:30-10:45 |
Break |
| 10:55-11:25 |
Stephen Soltoff (Beth Israel Deaconess Medical Center): Salivary gland signaling cascades |
| 11:25-11:55 |
Indu Ambudkar (NIDCR): Function of TRP channels in Ca2+ entry |
| 12:00-1:00 |
Lunch |
| 1:00-2:30 |
Poster Session: Co-chairs and Poster-Abstract Judges:Maria Kukuruzinska (Boston Univ), Mira Edgerton (SUNY Buffalo), Anil Menon (Univ of Cincinnati) |
| 2:45-5:45 |
Session III: The Epithelial Fluid Secretion Mechanism
Co-Chairs: Ted Begenisich & Shmuel Muallem |
| 2:45-3:15 |
Edmund Crampin (Auckland): Part II - A systems biology approach to secretion |
| 3:15-3:45 |
James Melvin (Univ Rochester): Cl channels and fluid secretion |
| 3:45-4:15 |
Ted Begenisich (Univ Rochester): K channel function / interaction of Slo and IK1 |
| 4:15-4:30 |
Break |
| 4:40-5:10 |
Shmuel Muallem (UT Southwestern): Ca2+ entry in Ca2+ signaling and disease |
| 5:10-5:40 |
Marshall Montrose (Univ Cincinnati): Epithelial barrier and GI function |
| 5:45-7:00 |
Dinner |
| 7:15-8:00 |
Keynote Speaker – William H. Bowen Lectureship
Larry Tabak (NIDCR): How Ira’s protein led me down a sugar coated trail |
| 8:00-9:00 |
Reception |
Saturday June 28
| 8:00-8:45 |
Breakfast |
| 9:00-12:00 |
Session IV: Saliva – Biomarkers / Structure and Function
Co-Chairs: Daniel Malamud & Stefan Ruhl |
| 9:00-9:30 |
Daniel Malamud (NYU): Update on oral-based diagnostics for systemic diseases |
| 9:30-10:00 |
Ignacio Sanz (Univ Rochester): B cells and the salivary glands. Biomarker applications |
| 10:00-10:30 |
Stefan Ruhl (SUNY-Buffalo): A proteomics-based search for bacterial recognition sites in human saliva |
| 10:30-10:45 |
Break |
| 10:55-11:25 |
Libuse Bobek (SUNY-Buffalo): Antimicrobial activity of MUC7 peptides |
| 11:25-11:55 |
Michel Koo (Univ Rochester): Saliva-bacterial interactions - Influences on S. mutans
biofilm formation |
| 12:00 |
Boxed lunches available |