Contact Info

Photo of Anne Luebke
Anne E. Luebke, Ph.D. Department of Biomedical Engineering University of Rochester work Box 603 601 Elmwood Ave Rochester, NY 14642 office: MC 6-8547 p +1-585-273-1635 f +1-585-276-5334

Anne Luebke - Current Research

Photomicrographs

Picture of project

Photomicrographs of whole mounts of b -galactosidase immunostained [E1 - , E3 - , pol - ] portions of cochlear turns at 8 d post-perfusion A: Adenovirus infection with lacZ expression driven by the CMV promoter stained outer hair cells (OHCs) in the low-frequency regions (apical portions) of the cochlea. B. No lacZ expression was detected in hair cells of the corresponding right (non-perfused) contralateral ear over the comparable low-frequency regions of the cochlea. C: Adenovirus infection with lacZ expression driven by the CMV promoter outer hair cells (OHCs) in the high-frequency regions (basal portions) of the cochlea. D: Again, no lacZ expression was detected in hair cells of the related right (non-perfused) contralateral ear, over the comparable high-frequency regions (basal portions) of the cochlea. E and F: Plastic-embedded cross-section of the cochlear whole-mount shown in 3C. All scale bars represent 20 m m unless noted otherwise.