Anne Luebke - Current Research
α9 nAChR overexpression
α9 nAChR overexpression reduces permanent noise induced damage. a: Protective effects of the transgene for an exposure designed to cause permanent threshold shift (PTS): 2 hr exposure to an 8-16 kHz noise band at 110 dB SPL. When measured 1 wk post exposure, mean PTS was significantly larger in wildtypes than in transgenics. b: Protective effects plotted for 3 different frequencies as a function of level. Data in both panels are expressed as group means ± s.e.m.