Research

Current Research

  1. ULAB07040- Identifying Biomarkers of Thromboembolism in Colrectal and Other Cancer Patients Receiving Bevacizumab: A Pilot Study
  2. URCC I2706 - Protocol CV 185027: A Randomized, Double-blind, Placebo-controlled Study of Apixaban for the Prevention of Thromboembolic Events in Patients Undergoing Treatment for Advance Cancer: A Phase 2 Pilot Study
  3. UMLT08006- Identifyling Incidence and Biomarkers of Venous Thromboembolism in High-Risk Cohort of Patients Initiating a New Chemotherapy Regimen.
  4. U1706-Percieve- Prospective Registry of Cancer and Events Involving Venous Thromboembolism.
  5. ULABO8113- A Laboratory Study in Ambulatory Cancer Patients at Low or Intermediate Risk for Venous Thromboembolism.

Recent Publications

  1. Connolly GC, Khorana AA.  Risk stratification for cancer-associated venous thromboembolism.  Best Pract Res Clin Haematol.  2009.  Mar 22 (1): 35-47
  2. Sousou T, Khorana AA.  New insights into cancer-associated thrombosis.  Arterioscler Thromb Vasc Biol.  2009 Mar 29 (3): 316-20.
  3. Yao JL, Ryan CK, Francis CW, Kohli M, Taubman MB, Khorana AA.  Tissue Factor and VEGF expression in prostate carcinoma: a tissue microarray study.  Cancer Invest 2009 May. 27 (4): 430-4.
  4. Khorana AA, Francis CW, Culakova E, Refaai M, Blumberg N and Lyman GH. Blood Transfusions, Thrombosis and Mortality in Hospitalized Cancer Patients.  Arch Int Med 2008. Nov 168 (21): 2377-81
  5. Khorana AA, Francis CW, Menzies KE, Wang JG, Hyrien O, Hathcock J, Mackman N, Taubman MB.  Plasma tissue factor may be predictive of venous thromboembolism in pancreatic cancer.   J Thromb Haemost.  2008.  Nov 6(11): 1983-5
  6. Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW.  Development and validation of a predictive model for chemotherapy-associated thrombosis. Blood. May 15;111(10);4902-7.
  7. Khorana AA. Risk factors, biomarkers and a risk model for cancer-associated thrombosis. Am Soc Clin Oncol Education Book 2008 (in press)
  8. Connolly GC, Chen R, Hyrien O, Mantry P, Bozorgzadeh A, Abt P, Khorana AA.  Incidence, risk factors and consequences of portal vein and systemic thromboses in hepatocellular carcinoma.  Thromb Res 2008. 122 (3):299-306.
  9. Khorana AA. The NCCN Clinical Practice Guidelines on Venous Thromboembolic Disease: Strategies for Improving VTE Prophylaxis in Hospitalized Cancer Patients.  The Oncologist 2007 Nov;12(11):1361-70.
  10. Khorana AA, Rao MV.  Approaches to risk-stratifying cancer patients for venous thromboembolism.  Thromb Res 2007;120 Suppl 2:S41-50.
  11. Lyman GH, Khorana AA, Falanga A, et al. American Society of Clinical Oncology guideline: recommendations for venous thromboembolism prophylaxis and treatment in patients with cancer. J Clin Oncol. 2007 Dec 1;25(34):5490-505.
  12. Khorana AA, Francis CW, Culakova E, Kuderer NM, Lyman GH.  Frequency, Risk Factors and Trends for Venous Thromboembolism Among Hospitalized Cancer Patients.  Cancer 2007 Nov 15;110(10):2339-46
  13. Kuderer NM, Khorana AA, Francis CW and Lyman GH. A Meta-Analysis and Systematic Review of the Efficacy and Safety of Anticoagulants as Cancer Treatment: Impact on Survival and Bleeding Complications.Cancer 2007 Sep 1;110(5):1149-61.
  14. Khorana AA, Ahrendt SA, Ryan CK, Francis CW, Hruban RH, Hu YC, Hostetter G, Harvey J, Taubman MB. Tissue Factor Expression, Angiogenesis and Thrombosis in Pancreatic Cancer. Clin Cancer Res 2007 May 15;13(10):2870-5.
  15. Khorana AA, Francis CW, Culakova E, Kuderer NM, Lyman GH. Thromboembolism is a leading cause of death in cancer patients receiving outpatient chemotherapy. J Thromb Haemost 2007 Mar;5(3):632-4.
  16. Komrokji RS, Uppal NP, Khorana AA, Lyman GH, Kaplan KL, Fisher RI, and Francis CW. Venous Thromboembolism in Patients with Diffuse Large B Cell Lymphoma. Leukemia and Lymphoma 2006 Jun;47(6):1029-33.
  17. Khorana AA, Francis CW, Culakova E, Fisher RI, Kuderer NM, Lyman GH. Thromboembolism in Hospitalized Neutropenic Cancer Patients. Journal of Clinical Oncology 2006 Jan 20;24(3):484-90.
  18. Sahni A, Khorana AA, Baggs RB, Peng H and Francis CW. FGF-2 Binding To Fibrin(ogen) Is Required For Augmented Angiogenesis. Blood 2006 Jan 1;107(1):126-31.
  19. Khorana AA, Francis CW, Culakova E, Lyman GH. Risk Factors for Chemotherapy-Associated Venous Thromboembolism in a Prospective Observational Study. Cancer, 2005 Dec 15;104(12):2822-9.

Cancer-Associated Thrombosis Information