Clinical and Translational Sciences Core Co-Directors: Amneris Luque, M.D. and James McMahon, Ph.D. This Core provides expertise and services to facilitate design, implementation and conduct of HIV/AIDS prevention, detection and treatment research. This core offers: study coordinator, patient access and sample collection services, regulatory and grant administration support, access to NIAID clinical research networks, support with international collaborations, study participation recruitment and community outreach and education. Study Coordinator/Patient Access and Sample Collection Services Assistance with recruitment, screening and referral of subjects and study coordination support Biological sample collection and conduct of minimal risk research Access to HIV+ patient data registry populated from medical records of patients attending the adult HIV clinic Regulatory and Grant Administration Training and Support This Core provides guidance regarding the involvement of human subjects in HIV/AIDS research including: Grant application support and information on NIH and URMC related policies and procedures Developing Human Subject Protection Plans IRB approval process, amendments, annual review Consultative Services in Clinical and Translational Research Assistance with development of project-specific strategies for community engagement and advice on how to access diverse, hard-to-reach populations Access to NIAID funded Clinical Research Networks: HIV Clinical Trials Unit and URMC Infectious Disease Division HVTN and ACTG Clinical Research Sites URMC Adult HIV Clinic and IMPAACT Clinical Trials AIDS Care and Monroe County STD Clinic Community Outreach and Education Coordinate community-based research and provide research advocacy and infrastructure support Support various activities promoting community outreach and education including: Community Advisory Board World AIDS Day Events Rochester Faith Collaborative Grassroot Soccer Rochester This Core assists CFAR investigators in collaborative projects with colleagues at The Desmond Tutu HIV Center at the University of Cape Town and the Perinatal HIV Reserach Unit at the University of Witwatersrand in South Africa as well as access to the South African Wellness Database for analysis and publicaction. For information about International Projects, please contact Michael Keefer.