Mondays, November 2013


November 4, 2013 ( Monday )

Other Events & Dates
11:30am - 12:30pm
Regulatory Science Seminar: "Model-Based Drug Development: A Biomedical Process for Clinical and Translational Science"

Save the date for a Regulatory Science seminar entitled, "Model-Based Drug Development: A Biomedical Process for Clinical and Translational Science." The seminar will be presented by Dr. Larry Lesko, Director, Center for Pharmacometrics and Systems Pharmacology, University of Florida; and Former Director, Office of Clinical Pharmacology, Center for Drug Evaluation and Research, FDA.

Location:  Helen Wood Hall Auditorium (1W-304)

Posted by:  Megan Mack, Office of Research Alliances, 24-Oct-13 1:13pm ET


Research Meetings
12:00pm - 1:00pm
Department of Biology Donut Talk

TBA

TBA

Location:  Hutchison 473

Posted by:  Deborah Lawrence, Biology, 22-Aug-13 12:51pm ET


Research Meetings
12:00pm - 1:00pm
Microbiology & Immunology Seminar Series

Co-Sponsored by the CFAR - Center for AIDS Research & the HIV Training Grant

Avindra Nath, Ph.D., Senior Investigator, Clinical Director of NINDS, the Director of the Translational Neuroscience Center and Chief of the Section of Infections of the Nervous System Section of Infections of the Nervous Systems, NIH

Title: Immune Reconstitution Syndrome with HIV Infection in the Brain

Host: Harris Gelbard

Research Abstract: Despite successful antiretroviral therapy, some patients develop an inflammation in the brain mediated by lymphocytes. I will discuss the clinical features, pathological findings, pathophysiology and treatment options of this syndrome. http://neuroscience.nih.gov/Lab.asp?Org_ID=568

Location:  K-307 (Room 3-6408)

Posted by:  Corrine Aleese, Micro & Immunolgy, 25-Sep-13 10:23am ET


Other Events & Dates
4:00pm - 5:00pm
Physical Seminar

Title: "Nanoparticle-cell interactions: Importance of protein structure"

Speaker: Professor Christine Payne Georgia Tech University School of Chemistry and Biochemistry

Host: Todd Krauss

Location:  Hutchison Hall 473

Posted by:  Marguerite Weston, Chemistry, 11-Oct-13 9:42am ET


November 11, 2013 ( Monday )

Research Meetings
12:00pm - 1:00pm
Microbiology & Immunology Seminar Series

Vanessa Sperandio, Ph.D., Professor of Microbiology and of Biochemistry, University of Texas Southwestern Medical Center

Title: Chemical signaling in bacterial/host interactions

Host: José Lemos & Michelle Dziejman

Research Abstract: Different chemical signaling systems shape bacterial/host relationships towards commensalism or pathogenesis. Enterohemorrhagic E. coli (EHEC) is a deadly food borne pathogen that causes hemorrhagic colitis worldwide. The main reservoir for EHEC is cattle herds. EHEC colonizes the recto anal junction (RAJ) of cattle, forming attaching and effacing (AE) lesions employing the locus of enterocyte effacement (LEE) genes. Additionally, EHEC also requires the glutamate acid resistance (gad) system to survive the acidic stomachs of these animals and successfully colonize the RAJ. Coordinated expression of the LEE and gad genes is achieved through SdiA, which is a transcription factor that functions as a receptor for acyl-homoserine lactones (AHL). Although E. coli (including EHEC) does not produce AHLs, they have the ability to respond to these signals through SdiA. SdiA senses AHLs produced by the rumminal microbiota affect LEE and gad expression through SdiAto promote EHEC's cattle colonization. http://profiles.utsouthwestern.edu/profile/50556/vanessa-sperandio.html

Location:  Ryan Case Method Room (1-9576)

Posted by:  Corrine Aleese, Micro & Immunolgy, 25-Sep-13 10:28am ET


Other Events & Dates
4:00pm - 5:00pm
Inorganic Seminar

Title: From CC agostic interactions to CH bond activation

Speaker: Professor Michel Etienne

Universite de Toulouse, Laboratoire de Chimie de Coordination du CNRS

Hosted by Professor William Jones, jones@chem.rochester.edu

Location:  Hutchison Hall 473

Posted by:  Marguerite Weston, Chemistry, 14-Oct-13 3:22pm ET


November 18, 2013 ( Monday )

Other Events & Dates
Physical Seminar

Title: Partition Density Functional Theory

Speaker: Professor Adam Wasserman

Department of Chemistry, Purdue University

Host: Professor Ignacio Franco

Location:  Hutchison Hall 473

Posted by:  Marguerite Weston, Chemistry, 16-Oct-13 10:14am ET


Research Meetings
12:00pm - 1:00pm
Department of Biology Donut Talk

Dr. John Thompson, UC Santa Cruz "The assembly of coevolving interactions"

Location:  Hutchison 473

Posted by:  Deborah Lawrence, Biology, 4-Nov-13 1:13pm ET


Research Meetings
12:00pm - 1:00pm
Microbiology & Immunology Seminar Series

Gerardo R. Vasta, Ph.D., Professor of Microbiology and Immunology, University of Maryland School of Medicine

Title: "The sweet tooth of innate immunity: Lectins as self/non-self recognition proteins"

Host: Jacques Robert

Seminar Abstract: Although lectins display a limited diversity in recognition, the presence of tandemly arrayed carbohydrate recognition domains (CRDs), of chimeric structures displaying distinct CRDs, of polymorphic genes resulting in multiple isoforms, and in some cases, of a considerable recognition plasticity of their carbohydrate binding sites, significantly expand the lectin ligand-recognition spectrum and lectin functional diversification. In this regard, analysis of structural/functional aspects of F-lectins—the most recently identified lectin family characterized by a unique CRD sequence motif, a distinctive structural fold, and nominal specificity for L-Fuc—has led to a greater understanding of non-self recognition by proteins with tandemly arrayed CRDs. In contrast, galectins were initially considered to bind endogenous ("self") glycans and mediate developmental processes, including cell differentiation and tissue organization or regeneration. In the past few years, numerous studies have described the diverse regulatory effects of galectins on immune homeostasis and cancer. More recently, however, evidence has accumulated to support the notion that galectins also bind exogenous ("non-self") glycans on the surface of potentially pathogenic microbes, parasites, and fungi, suggesting that galectins could function as pattern recognition receptors (PRRs). Galectins, however, can bind similar self/non-self molecular patterns on host and microbial cells. Furthermore, although some galectins can bind and kill bacteria, thereby displaying activity as innate immune recognition and effector factors, it appears that in most cases galectin-mediated recognition favors the potential pathogen rather than the host. Therefore, some galectins do not fit the definition of PRRs, underscoring the significant gaps in our knowledge about the structural and functional diversity, subcellular targeting, localization, and secretion of the galectin repertoire components in any given species, and the host-parasite co-evolutionary processes that have resulted in such interactions. http://medschool.umaryland.edu/FACULTYRESEARCHPROFILE/viewprofile.aspx?id=22021

Location:  K-307 (Room 3-6408)

Posted by:  Corrine Aleese, Micro & Immunolgy, 25-Sep-13 10:34am ET


November 25, 2013 ( Monday )

Research Meetings
12:00pm - 1:00pm
Microbiology & Immunology Seminar Series

Co-Sponsored by the CFAR - Center for AIDS Research & the HIV Training Grant

Avindra Nath, Ph.D., Senior Investigator, Clinical Director of NINDS, the Director of the Translational Neuroscience Center and Chief of the Section of Infections of the Nervous System Section of Infections of the Nervous Systems, NIH

Title: Immune Reconstitution Syndrome with HIV Infection in the Brain

Host: Harris Gelbard

Research Abstract: Despite successful antiretroviral therapy, some patients develop an inflammation in the brain mediated by lymphocytes. I will discuss the clinical features, pathological findings, pathophysiology and treatment options of this syndrome. http://neuroscience.nih.gov/Lab.asp?Org_ID=568

Location:  K-307 (Room 3-6408)

Posted by:  Corrine Aleese, Micro & Immunolgy, 25-Sep-13 10:22am ET


Research Meetings
12:00pm - 1:00pm
Microbiology & Immunology Seminar Series

Anders P. Hakansson, Ph.D., Assistant Professor of Microbiology and Immunology, The Witebsky Center for Microbial Pathogenesis & Immunology, University of Buffalo

Title: To be announced

Hosts: Steve Gill & Michelle Dziejman

Research Interests: My laboratory is focused on investigating the pathogenesis of the gram-positive, extracellular pathogen Streptococcus pneumoniae (pneumococcus). S. pneumoniae is one of the leading causes of morbidity and mortality from respiratory tract and invasive infections in children and the elderly worldwide. Pneumococci effectively colonize the human nasopharynx and cause infections such as pneumonia, acute otitis media (AOM), meningitis and sepsis by disseminating to otherwise sterile sites.

http://www.smbs.buffalo.edu/wcmpi/Faculty/hakansson.htm

Location:  K-307 (Room 3-6408)

Posted by:  Corrine Aleese, Micro & Immunolgy, 25-Sep-13 11:20am ET


Research Meetings
1:00pm - 2:00pm
Neurodegenerative Disease: Challenges, Opportunities, Innovation and Collaboration

Steven Finkbeiner, M.D., Ph.D.


Senior Investigator and Associate Director, Gladstone Institute of Neurological Disease; The J. David Gladstone Institutes, University of California, San Francisco

Faculty Candidate, Scientific Director, DelMonte Institute for Neuromedicine

Location:  Class of '62 Auditorium, Rm. #G-9425

Posted by:  Sharon Kubiak, 22-Nov-13 2:04pm ET


Other Events & Dates
1:15pm - 2:15pm
Chemistry PhD Defense

Title: Analysis of RNA Secondary Structure: Common Themes in Spliced Segments of Influenza A, B, and C

Speaker: Lumbini Indeewari Dela-Moss, Turner Group

Location:  2-110D Dewey Hall

Posted by:  Marguerite Weston, Chemistry, 13-Nov-13 4:03pm ET

 
 
http://www.urmc.rochester.edu/calendar/index.html