12:00pm - 1:00pm|
Department of Microbiology & Immunology Seminar Series
Gerlinde Van de Walle, DVM, Ph.D.
Assistant Professor of Viral Pathogenesis, Baker Institute for Animal Health, Cornell University, College of Veterinary Medicine
" Explant culture systems: useful tools to study herpesvirus pathogenesis"
Host: Brian Ward
Seminar Abstract: Herpesvirus infections are an important cause of disease in humans and many other animal species, including horses, dogs and cats. Infection occurs via mucosal surfaces of the respiratory and genital tracts or via epithelial surfaces such as the cornea of the eye. Our laboratory focuses on the development of physiologically relevant in vitro models to study herpesvirus pathogenesis. More specifically, we use tissue and organ explant models in which the three-dimensional structures and normal cell-cell contacts are maintained. These explant culture systems closely mimic the in vivo situation and, therefore, are a useful stepping-stone bridging in vitro and in vivo models. These models can be used to study viral replication kinetics and virus-host interactions, as well as to evaluate novel vaccines and antivirals.
|Location: ||K-307 Auditorium, 3-6408|
Posted by: Nicole Beaumont, Micro & Immunolgy, 10-Nov-14 11:24am ET