Publications

Showing 91 of 91 journal articles.

Azadniv M; Bowers WJ; Topham DJ; Crispe IN. "CD4+ T cell effects on CD8+ T cell location defined using bioluminescence." PloS one. 2011; 6(1):e16222. Epub 2011 Jan 20.

Hunter JM; Bowers WJ; Maarouf CL; Mastrangelo MA; Daugs ID; Kokjohn TA; Kalback WM; Luehrs DC; Valla J; Beach TG; Roher AE. "Biochemical and morphological characterization of the A?PP/PS/tau triple transgenic mouse model and its relevance to sporadic alzheimer's Disease." Journal of Alzheimer's disease : JAD. 2011; 27(2):361-76.

García-Alías G; Petrosyan HA; Schnell L; Horner PJ; Bowers WJ; Mendell LM; Fawcett JW; Arvanian VL. "Chondroitinase ABC combined with neurotrophin NT-3 secretion and NR2D expression promotes axonal plasticity and functional recovery in rats with lateral hemisection of the spinal cord." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2011; 31(49):17788-99.

Philippidou P; Valdez G; Akmentin W; Bowers WJ; Federoff HJ; Halegoua S. "Trk retrograde signaling requires persistent, Pincher-directed endosomes." Proceedings of the National Academy of Sciences of the United States of America. 2011; 108(2):852-7. Epub 2010 Dec 27.

Desai MK; Guercio BJ; Narrow WC; Bowers WJ. "An Alzheimer's disease-relevant presenilin-1 mutation augments amyloid-beta-induced oligodendrocyte dysfunction." Glia. 2011; 59(4):627-40. Epub 2011 Feb 03.

Bowers WJ; Breakefield XO; Sena-Esteves M. "Genetic therapy for the nervous system." Human molecular genetics. 2011; 20(R1):R28-41. Epub 2011 Mar 23.

Montgomery SL; Bowers WJ. "Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System." Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2011; Epub 2011 Jul 05.

Domm W; Brooks L; Chung HL; Feng C; Bowers WJ; Watson G; McGrath JL; Dewhurst S. "Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual barrier." Vaccine. 2011; 29(40):7080-9. Epub 2011 Jul 27.

Montgomery SL; Mastrangelo MA; Habib D; Narrow WC; Burrell SA; Wright TW; Bowers WJ. "Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-? suppressive therapeutic strategies in the brain." The American journal of pathology. 2011; 179(4):2053-70. Epub 2011 Aug 09.

Schnell L; Hunanyan AS; Bowers WJ; Horner PJ; Federoff HJ; Gullo M; Schwab ME; Mendell LM; Arvanian VL. "Combined delivery of Nogo-A antibody, neurotrophin-3 and the NMDA-NR2d subunit establishes a functional 'detour' in the hemisected spinal cord." The European journal of neuroscience. 2011; 34(8):1256-67. Epub 2011 Oct 13.

de Silva S; Bowers WJ. "Targeting the central nervous system with herpes simplex virus / Sleeping Beauty hybrid amplicon vectors." Current gene therapy. 2011; 11(5):332-40.

Fong S; Chan MK; Fong A; Bowers WJ; Kelly KJ. "Viral vector-induced expression of bone morphogenetic protein 2 produces inhibition of tumor growth and bone differentiation of stem cells." Cancer gene therapy. 2010; 17(2):80-5. Epub 2009 Oct 16.

de Silva S; Mastrangelo MA; Lotta LT; Burris CA; Federoff HJ; Bowers WJ. "Extending the transposable payload limit of Sleeping Beauty (SB) using the Herpes Simplex Virus (HSV)/SB amplicon-vector platform." Gene therapy. 2010; 17(3):424-31. Epub 2009 Oct 29.

Park KM; Yule DI; Bowers WJ. "Impaired TNF-alpha control of IP3R-mediated Ca2+ release in Alzheimer's disease mouse neurons." Cellular signalling. 2010; 22(3):519-26.

Xiong Y; Coombes CE; Kilaru A; Li X; Gitler AD; Bowers WJ; Dawson VL; Dawson TM; Moore DJ. "GTPase activity plays a key role in the pathobiology of LRRK2." PLoS genetics. 2010; 6(4):e1000902. Epub 2010 Apr 08.

Park KM; Bowers WJ. "Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction." Cellular signalling. 2010; 22(7):977-83. Epub 2010 Jan 21.

Kells AP; Eberling J; Su X; Pivirotto P; Bringas J; Hadaczek P; Narrow WC; Bowers WJ; Federoff HJ; Forsayeth J; Bankiewicz KS. "Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2010; 30(28):9567-77.

Ryan DA; Narrow WC; Federoff HJ; Bowers WJ. "An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies." Journal of neuroscience methods. 2010; 190(2):171-9. Epub 2010 May 07.

Ryan DA; Mastrangelo MA; Narrow WC; Sullivan MA; Federoff HJ; Bowers WJ. "Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice." Molecular therapy : the journal of the American Society of Gene Therapy. 2010; 18(8):1471-81. Epub 2010 Jun 15.

Desai MK; Mastrangelo MA; Ryan DA; Sudol KL; Narrow WC; Bowers WJ. "Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target." The American journal of pathology. 2010; 177(3):1422-35. Epub 2010 Aug 09.

Lee BD; Shin JH; Vankampen J; Petrucelli L; West AB; Ko HS; Lee YI; Maguire-Zeiss KA; Bowers WJ; Federoff HJ; Dawson VL; Dawson TM. "Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease." Nature medicine. 2010; 16(9):998-1000. Epub 2010 Aug 22.

de Silva S; Mastrangelo MA; Lotta Jr LT; Burris CA; Izsvák Z; Ivics Z; Bowers WJ. "Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo." Human gene therapy. 2010; 21(11):1603-13. Epub 2010 Oct 22.

de Silva S; Lotta Jr LT; Burris CA; Bowers WJ. "Virion-associated cofactor high-mobility group DNA-binding protein-1 facilitates transposition from the herpes simplex virus/Sleeping Beauty amplicon vector platform." Human gene therapy. 2010; 21(11):1615-22. Epub 2010 Oct 07.

Bancos S; Cao Q; Bowers WJ; Crispe IN. "Dysfunctional memory CD8+ T cells after priming in the absence of the cell cycle regulator E2F4." Cellular immunology. 2009; 257(1-2):44-54.

Sudol KL; Mastrangelo MA; Narrow WC; Frazer ME; Levites YR; Golde TE; Federoff HJ; Bowers WJ. "Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease." Molecular therapy : the journal of the American Society of Gene Therapy. 2009; 17(12):2031-40. Epub 2009 Jul 28.

de Silva S; Bowers WJ. "Herpes Virus Amplicon Vectors." Viruses. 2009; 1(3):594-629.

Desai MK; Sudol KL; Janelsins MC; Mastrangelo MA; Frazer ME; Bowers WJ. "Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology." Glia. 2009; 57(1):54-65.

Daubeuf S; Singh D; Tan Y; Liu H; Federoff HJ; Bowers WJ; Tolba K. "HSV ICP0 recruits USP7 to modulate TLR-mediated innate response." Blood. 2009; 113(14):3264-75. Epub 2008 Oct 24.

Federoff HJ; Chiu YG; Bowers WJ; Lim ST; Ryan DA. "Effects of herpes simplex virus amplicon transduction on murine dendritic cells." Human gene therapy. 2009; 20(5):442-52.

Fiandaca MS; Varenika V; Eberling J; McKnight T; Bringas J; Pivirotto P; Beyer J; Hadaczek P; Bowers W; Park J; Federoff H; Forsayeth J; Bankiewicz KS. "Real-time MR imaging of adeno-associated viral vector delivery to the primate brain." NeuroImage. 2009; 47 Suppl 2():T27-35. Epub 2008 Nov 27.

Park KM; Yule DI; Bowers WJ. "Tumor necrosis factor-alpha-mediated regulation of the inositol 1,4,5-trisphosphate receptor promoter." The Journal of biological chemistry. 2009; 284(40):27557-66. Epub 2009 Aug 07.

Mastrangelo MA; Sudol KL; Narrow WC; Bowers WJ. "Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice." The American journal of pathology. 2009; 175(5):2076-88. Epub 2009 Oct 01.

Mastrangelo MA; Bowers WJ. "Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice." BMC neuroscience. 2008; 9():81. Epub 2008 Aug 12.

Janelsins MC; Mastrangelo MA; Park KM; Sudol KL; Narrow WC; Oddo S; LaFerla FM; Callahan LM; Federoff HJ; Bowers WJ. "Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice." The American journal of pathology. 2008; 173(6):1768-82. Epub 2008 Oct 30.

Burris CA; de Silva S; Narrow WC; Casey AE; Lotta LT; Federoff HJ; Bowers WJ. "Hexamethylene bisacetamide leads to reduced helper virus-free HSV-1 amplicon expression titers via suppression of ICP0." The journal of gene medicine. 2008; 10(2):152-64.

Nechushtan H; Pham D; Zhang Y; Morgensztern D; Yi KH; Shin SU; Federoff HJ; Bowers WJ; Tolba KA; Rosenblatt JD. "Augmentation of anti-tumor responses of adoptively transferred CD8+T cells in the lymphopenic setting by HSV amplicon transduction." Cancer immunology, immunotherapy : CII. 2008; 57(5):663-75. Epub 2007 Oct 19.

Frazer ME; Hughes JE; Mastrangelo MA; Tibbens JL; Federoff HJ; Bowers WJ. "Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4." Molecular therapy : the journal of the American Society of Gene Therapy. 2008; 16(5):845-53. Epub 2008 Mar 11.

Park KM; Yule DI; Bowers WJ. "Tumor necrosis factor-alpha potentiates intraneuronal Ca2+ signaling via regulation of the inositol 1,4,5-trisphosphate receptor." The Journal of biological chemistry. 2008; 283(48):33069-79. Epub 2008 Oct 06.

Santos, K.; Sanfilippo, C.M.; Narrow, W.C.; Casey, A.E.; McDermott, M.; Federoff, H.J.; Bowers, W.J.; Dewhurst, S. "Infectivity of Herpes Simplex Virus Type-1 (HSV-1) amplicon vectors in dendritic cells is determined by the helper virus strain used for packaging". J Virol Meth. 2007; 145: 37-46.

Santos K; Duke CM; Rodriguez-Colon SM; Dakwar A; Fan S; Keefer MC; Federoff HJ; Frelinger JG; Bowers WJ; Dewhurst S. "Effect of promoter strength on protein expression and immunogenicity of an HSV-1 amplicon vector encoding HIV-1 Gag." Vaccine. 2007; 25(9):1634-46. Epub 2006 Nov 15.

Sortwell CE; Bowers WJ; Counts SE; Pitzer MR; Fleming MF; McGuire SO; Maguire-Zeiss KA; Federoff HJ; Collier TJ. "Effects of ex vivo transduction of mesencephalic reaggregates with bcl-2 on grafted dopamine neuron survival." Brain research. 2007; 1134(1):33-44. Epub 2006 Dec 28.

Peterson EB; Mastrangelo MA; Federoff HJ; Bowers WJ. "Neuronal specificity of HSV/sleeping beauty amplicon transduction in utero is driven primarily by tropism and cell type composition." Molecular therapy : the journal of the American Society of Gene Therapy. 2007; 15(10):1848-55. Epub 2007 Jul 24.

Azadniv M; Dugger K; Bowers WJ; Weaver C; Crispe IN. "Imaging CD8+ T cell dynamics in vivo using a transgenic luciferase reporter." International immunology. 2007; 19(10):1165-73. Epub 2007 Aug 14.

Yi KH; Nechushtan H; Bowers WJ; Walker GR; Zhang Y; Pham DG; Podack ER; Federoff HJ; Tolba KA; Rosenblatt JD. "Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo." Cancer research. 2007; 67(20):10027-37.

Duke CM; Maguire CA; Keefer MC; Federoff HJ; Bowers WJ; Dewhurst S. "HSV-1 amplicon vectors elicit polyfunctional T cell responses to HIV-1 Env, and strongly boost responses to an adenovirus prime." Vaccine. 2007; 25(42):7410-21. Epub 2007 Aug 30.

Arvanian VL; Bowers WJ; Anderson A; Horner PJ; Federoff HJ; Mendell LM. "Combined delivery of neurotrophin-3 and NMDA receptors 2D subunit strengthens synaptic transmission in contused and staggered double hemisected spinal cord of neonatal rat." Experimental neurology. 2006; 197(2):347-52. Epub 2005 Nov 11.

Bowers WJ; Mastrangelo MA; Howard DF; Southerland HA; Maguire-Zeiss KA; Federoff HJ. "Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector." Molecular therapy : the journal of the American Society of Gene Therapy. 2006; 13(3):580-8. Epub 2006 Jan 18.

Tyler CM; Wuertzer CA; Bowers WJ; Federoff HJ. "HSV amplicons: neuro applications." Current gene therapy. 2006; 6(3):337-50.

Halterman MW; Giuliano RE; Bowers WJ; Federoff HJ. "Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity." The journal of gene medicine. 2006; 8(11):1320-8.

Reinblatt M; Pin RH; Bowers WJ; Federoff HJ; Fong Y. "Herpes simplex virus amplicon delivery of a hypoxia-inducible soluble vascular endothelial growth factor receptor (sFlk-1) inhibits angiogenesis and tumor growth in pancreatic adenocarcinoma." Annals of surgical oncology. 2005; 12(12):1025-36. Epub 2005 Oct 25.

Gorantla S; Santos K; Meyer V; Dewhurst S; Bowers WJ; Federoff HJ; Gendelman HE; Poluektova L. "Human dendritic cells transduced with herpes simplex virus amplicons encoding human immunodeficiency virus type 1 (HIV-1) gp120 elicit adaptive immune responses from human cells engrafted into NOD/SCID mice and confer partial protection against HIV-1 challenge." Journal of virology. 2005; 79(4):2124-32.

Bowers WJ; Mastrangelo MA; Stanley HA; Casey AE; Milo LJ; Federoff HJ. "HSV amplicon-mediated Abeta vaccination in Tg2576 mice: differential antigen-specific immune responses." Neurobiology of aging. 2005; 26(4):393-407.

Corso TD; Torres G; Goulah C; Roy I; Gambino AS; Nayda J; Buckley T; Stachowiak EK; Bergey EJ; Pudavar H; Dutta P; Bloom DC; Bowers WJ; Stachowiak MK. "Assessment of viral and non-viral gene transfer into adult rat brains using HSV-1, calcium phosphate and PEI-based methods." Folia morphologica. 2005; 64(3):130-44.

Janelsins MC; Mastrangelo MA; Oddo S; LaFerla FM; Federoff HJ; Bowers WJ. "Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice." Journal of neuroinflammation. 2005; 2():23. Epub 2005 Oct 18.

Federoff HJ; Bowers WJ. "Immune shaping and the development of Alzheimer's disease vaccines." Science of aging knowledge environment : SAGE KE. 2005; 2005(46):pe35. Epub 2005 Nov 16.

Arvanian, V.L.; Bowers, W.J.; Petruska, J.C.; Motin, V.; Manuzon, H.; Narrow, W.C.; Federoff, H.J.; Mendell, L.M. "Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons." J. Neurophys.. 2004; 92: 2394-2404.

Wang H; Yu SW; Koh DW; Lew J; Coombs C; Bowers W; Federoff HJ; Poirier GG; Dawson TM; Dawson VL. "Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004; 24(48):10963-73.

Pin RH; Reinblatt M; Bowers WJ; Federoff HJ; Fong Y. "Herpes simplex virus amplicon delivery of a hypoxia-inducible angiogenic inhibitor blocks capillary formation in hepatocellular carcinoma." Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract. 2004; 8(7):812-22; discussion 822-3.

Snyder JE; Bowers WJ; Livingstone AM; Lee FE; Federoff HJ; Mosmann TR. "Measuring the frequency of mouse and human cytotoxic T cells by the Lysispot assay: independent regulation of cytokine secretion and short-term killing." Nature medicine. 2003; 9(2):231-5. Epub 2003 Jan 21.

Olschowka JA; Bowers WJ; Hurley SD; Mastrangelo MA; Federoff HJ. "Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS." Molecular therapy : the journal of the American Society of Gene Therapy. 2003; 7(2):218-27.

Bowers WJ; Olschowka JA; Federoff HJ. "Immune responses to replication-defective HSV-1 type vectors within the CNS: implications for gene therapy." Gene therapy. 2003; 10(11):941-5.

Wang X; Wiley RD; Evans TG; Bowers WJ; Federoff HJ; Dewhurst S. "Cellular immune responses to helper-free HSV-1 amplicon particles encoding HIV-1 gp120 are enhanced by DNA priming." Vaccine. 2003; 21(19-20):2288-97.

Zhang Y; Hong Y; Bounhar Y; Blacker M; Roucou X; Tounekti O; Vereker E; Bowers WJ; Federoff HJ; Goodyer CG; LeBlanc A. "p75 neurotrophin receptor protects primary cultures of human neurons against extracellular amyloid beta peptide cytotoxicity." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2003; 23(19):7385-94.

Harvey BK; Chang CF; Chiang YH; Bowers WJ; Morales M; Hoffer BJ; Wang Y; Federoff HJ. "HSV amplicon delivery of glial cell line-derived neurotrophic factor is neuroprotective against ischemic injury." Experimental neurology. 2003; 183(1):47-55.

Kyrkanides S; Miller JH; Bowers WJ; Federoff HJ. "Transcriptional and posttranslational regulation of Cre recombinase by RU486 as the basis for an enhanced inducible expression system." Molecular therapy : the journal of the American Society of Gene Therapy. 2003; 8(5):790-5.

Bowers, W.J.; Chen, X.; Guo, H.; Frisina, D.R.; Federoff, H.J.; Frisina, R.D.;. "Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea". Mol Ther. 2002; 6(1): Ganglion/drug effects/*physiopathology.

Bowers WJ; Federoff HJ. "Amyloid immunotherapy-engendered CNS inflammation." Neurobiology of aging. 2002; 23(5):675-6; discussion 683-4.

Maguire-Zeiss KA; Bowers WJ; Federoff HJ. "Somatic mosaic approaches and the aging brain." Neurobiology of aging. 2002; 23(5):977-84.

Wang SW; Mu X; Bowers WJ; Klein WH. "Retinal ganglion cell differentiation in cultured mouse retinal explants." Methods (San Diego, Calif.). 2002; 28(4):448-56.

Wang SW; Mu X; Bowers WJ; Kim DS; Plas DJ; Crair MC; Federoff HJ; Gan L; Klein WH. "Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth." Development (Cambridge, England). 2002; 129(2):467-77.

Halaby IA; Lyden SP; Davies MG; Roztocil E; Salamone LJ; Brooks AI; Green RM; Federoff HJ; Bowers WJ. "Glucocorticoid-regulated VEGF expression in ischemic skeletal muscle." Molecular therapy : the journal of the American Society of Gene Therapy. 2002; 5(3):300-6.

Hocknell PK; Wiley RD; Wang X; Evans TG; Bowers WJ; Hanke T; Federoff HJ; Dewhurst S. "Expression of human immunodeficiency virus type 1 gp120 from herpes simplex virus type 1-derived amplicons results in potent, specific, and durable cellular and humoral immune responses." Journal of virology. 2002; 76(11):5565-80.

Detrait ER; Bowers WJ; Halterman MW; Giuliano RE; Bennice L; Federoff HJ; Richfield EK. "Reporter gene transfer induces apoptosis in primary cortical neurons." Molecular therapy : the journal of the American Society of Gene Therapy. 2002; 5(6):723-30.

Mankodi A; Takahashi MP; Jiang H; Beck CL; Bowers WJ; Moxley RT; Cannon SC; Thornton CA. "Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy." Molecular cell. 2002; 10(1):35-44.

Yu SW; Wang H; Poitras MF; Coombs C; Bowers WJ; Federoff HJ; Poirier GG; Dawson TM; Dawson VL. "Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor." Science (New York, N.Y.). 2002; 297(5579):259-63.

Tolba KA; Bowers WJ; Eling DJ; Casey AE; Kipps TJ; Federoff HJ; Rosenblatt JD. "HSV amplicon-mediated delivery of LIGHT enhances the antigen-presenting capacity of chronic lymphocytic leukemia." Molecular therapy : the journal of the American Society of Gene Therapy. 2002; 6(4):455-63.

Tolba KA; Bowers WJ; Muller J; Housekneckt V; Giuliano RE; Federoff HJ; Rosenblatt JD. "Herpes simplex virus (HSV) amplicon-mediated codelivery of secondary lymphoid tissue chemokine and CD40L results in augmented antitumor activity." Cancer research. 2002; 62(22):6545-51.

Bowers WJ; Howard DF; Brooks AI; Halterman MW; Federoff HJ. "Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers." Gene therapy. 2001; 8(2):111-20.

Jackson M; Song W; Liu MY; Jin L; Dykes-Hoberg M; Lin CI; Bowers WJ; Federoff HJ; Sternweis PC; Rothstein JD. "Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins." Nature. 2001; 410(6824):89-93.

Chen X; Frisina RD; Bowers WJ; Frisina DR; Federoff HJ. "HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage." Molecular therapy : the journal of the American Society of Gene Therapy. 2001; 3(6):958-63.

Tolba KA; Bowers WJ; Hilchey SP; Halterman MW; Howard DF; Giuliano RE; Federoff HJ; Rosenblatt JD. "Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia." Blood. 2001; 98(2):287-95.

Ballas N; Battaglioli E; Atouf F; Andres ME; Chenoweth J; Anderson ME; Burger C; Moniwa M; Davie JR; Bowers WJ; Federoff HJ; Rose DW; Rosenfeld MG; Brehm P; Mandel G. "Regulation of neuronal traits by a novel transcriptional complex." Neuron. 2001; 31(3):353-65.

Maguire-Zeiss KA; Bowers WJ; Federoff HJ. "HSV vector-mediated gene delivery to the central nervous system." Current opinion in molecular therapeutics. 2001; 3(5):482-90.

Willis RA; Bowers WJ; Turner MJ; Fisher TL; Abdul-Alim CS; Howard DF; Federoff HJ; Lord EM; Frelinger JG. "Dendritic cells transduced with HSV-1 amplicons expressing prostate-specific antigen generate antitumor immunity in mice." Human gene therapy. 2001; 12(15):1867-79.

Bowers WJ; Howard DF; Federoff HJ. "Discordance between expression and genome transfer titering of HSV amplicon vectors: recommendation for standardized enumeration." Molecular therapy : the journal of the American Society of Gene Therapy. 2000; 1(3):294-9.

Brooks AI; Cory-Slechta DA; Bowers WJ; Murg SL; Federoff HJ. "Enhanced learning in mice parallels vector-mediated nerve growth factor expression in hippocampus." Human gene therapy. 2000; 11(17):2341-52.

Bowers WJ; Howard DF; Federoff HJ. "Gene therapeutic strategies for neuroprotection: implications for Parkinson's disease." Experimental neurology. 1997; 144(1):58-68.

Baglia LA; Bowers WJ; Ruddell A. "The avian C/EBPgamma gene encodes a highly conserved leucine zipper transcription factor." Gene. 1997; 190(2):297-302.

Bowers WJ; Baglia LA; Ruddel A. "Regulation of avian leukosis virus long terminal repeat-enhanced transcription by C/EBP-Rel interactions." Journal of virology. 1996; 70(5):3051-9.

Bowers WJ; Petrosino JF; Smith CD; Ruddell A. "Transcriptional regulation of ALV bursal lymphomagenesis." Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 1994; 8 Suppl 1():S211-3.

Bowers WJ; Ruddell A. "a1/EBP: a leucine zipper protein that binds CCAAT/enhancer elements in the avian leukosis virus long terminal repeat enhancer." Journal of virology. 1992; 66(11):6578-86.