Publications and Patents

Publications

Showing 33 of 33 journal articles.

Matthews TA; Abel A; Demme C; Sherman T; Pan PW; Halterman MW; Parkkila S; Nehrke K. "Expression of the CHOP-inducible carbonic anhydrase CAVI-b is required for BDNF-mediated protection from hypoxia." Brain research. 2014; 1543():28-37. Epub 2013 Nov 23.

Rininger A; Wayland A; Prifti V; Halterman MW. "Assessment of CA1 injury after global ischemia using supervised 2D analyses of nuclear pyknosis." Journal of neuroscience methods.. 2012; 207(2):181-8. Epub 2012 Apr 21.

Rininger A; Dejesus C; Totten A; Wayland A; Halterman MW. "MKP-1 antagonizes C/EBP? activity and lowers the apoptotic threshold after ischemic injury." Cell death and differentiation. 2012; 19(10):1634-43. Epub 2012 Apr 20.

Qazi A; Halterman MW; Mi Z; Zhang T; Schor NF. "Chopper is prodeath regardless of the effect of p75ICD on sensitivity to oxidative stress." Oxidative medicine and cellular longevity.. 2011; 2011():391659. Epub 2011 Sep 05.

Segel GB; Halterman MW; Lichtman MA. "The paradox of the neutrophil's role in tissue injury." Journal of leukocyte biology.. 2011; 89(3):359-72. Epub 2010 Nov 19.

Halterman MW. "An improved method for the study of apoptosis-related genes using the tet-on system." Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. 2011; 16(3):332-7. Epub 2011 Feb 18.

Halterman MW; Gill M; Dejesus C; Ogihara M; Schor NF; Federoff HJ. "The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death." The Journal of biological chemistry.. 2010; 285(28):21329-40. Epub 2010 May 06.

Halterman MW; Giuliano R; Dejesus C; Schor NF. "In-tube transfection improves the efficiency of gene transfer in primary neuronal cultures." Journal of neuroscience methods.. 2009; 177(2):348-54. Epub 2008 Oct 30.

Halterman MW; De Jesus C; Rempe DA; Schor NF; Federoff HJ. "Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons." Molecular and cellular neurosciences. 2008; 38(2):125-37. Epub 2008 Feb 13.

Halterman MW; Vates GE; Riggs G. "Teaching NeuroImage: tremor in aqueductal stenosis and response to endoscopic third ventriculostomy." Neurology.. 2007; 68(19):E29-31.

Halterman MW; Giuliano RE; Bowers WJ; Federoff HJ. "Improved HSV-1 amplicon packaging using virion host shutoff mutants lacking mRNAse activity." The journal of gene medicine.. 2006; 8(11):1320-8.

Abeysinghe HR; Pollock SJ; Guckert NL; Veyberman Y; Keng P; Halterman M; Federoff HJ; Rosenblatt JP; Wang N. "The role of the THY1 gene in human ovarian cancer suppression based on transfection studies." Cancer genetics and cytogenetics.. 2004; 149(1):1-10.

Detrait ER; Bowers WJ; Halterman MW; Giuliano RE; Bennice L; Federoff HJ; Richfield EK. "Reporter gene transfer induces apoptosis in primary cortical neurons." Molecular therapy : the journal of the American Society of Gene Therapy.. 2002; 5(6):723-30.

Delman KA; Zager JS; Bennett JJ; Malhotra S; Ebright MI; McAuliffe PF; Halterman MW; Federoff HJ; Fong Y. "Efficacy of multiagent herpes simplex virus amplicon-mediated immunotherapy as adjuvant treatment for experimental hepatic cancer." Annals of surgery.. 2002; 236(3):337-42; discussion 342-3.

Bowers WJ; Howard DF; Brooks AI; Halterman MW; Federoff HJ. "Expression of vhs and VP16 during HSV-1 helper virus-free amplicon packaging enhances titers." Gene therapy.. 2001; 8(2):111-20.

Tolba KA; Bowers WJ; Hilchey SP; Halterman MW; Howard DF; Giuliano RE; Federoff HJ; Rosenblatt JD. "Development of herpes simplex virus-1 amplicon-based immunotherapy for chronic lymphocytic leukemia." Blood.. 2001; 98(2):287-95.

Zager JS; Delman KA; Malhotra S; Ebright MI; Bennett JJ; Kates T; Halterman M; Federoff H; Fong Y. "Combination vascular delivery of herpes simplex oncolytic viruses and amplicon mediated cytokine gene transfer is effective therapy for experimental liver cancer." Molecular medicine (Cambridge, Mass.). 2001; 7(8):561-8.

Carew JF; Kooby DA; Halterman MW; Kim SH; Federoff HJ; Fong Y. "A novel approach to cancer therapy using an oncolytic herpes virus to package amplicons containing cytokine genes." Molecular therapy : the journal of the American Society of Gene Therapy.. 2001; 4(3):250-6.

Bennett JJ; Kooby DA; Delman K; McAuliffe P; Halterman MW; Federoff H; Fong Y. "Antitumor efficacy of regional oncolytic viral therapy for peritoneally disseminated cancer." Journal of molecular medicine (Berlin, Germany). 2000; 78(3):166-74.

D'Angelica M; Karpoff H; Halterman M; Ellis J; Klimstra D; Edelstein D; Brownlee M; Federoff H; Fong Y. "In vivo interleukin-2 gene therapy of established tumors with herpes simplex amplicon vectors." Cancer immunology, immunotherapy : CII.. 1999; 47(5):265-71.

Kutubuddin M; Federoff HJ; Challita-Eid PM; Halterman M; Day B; Atkinson M; Planelles V; Rosenblatt JD. "Eradication of pre-established lymphoma using herpes simplex virus amplicon vectors." Blood.. 1999; 93(2):643-54.

Brooks AI; Halterman MW; Federoff HJ. "Focal hippocampal gain of NGF function elicits specific septal cholinergic reorganization." Neuroreport. 1999; 10(2):337-44.

White SM; Renda M; Nam NY; Klimatcheva E; Zhu Y; Fisk J; Halterman M; Rimel BJ; Federoff H; Pandya S; Rosenblatt JD; Planelles V. "Lentivirus vectors using human and simian immunodeficiency virus elements." Journal of virology.. 1999; 73(4):2832-40.

Carew JF; Kooby DA; Halterman MW; Federoff HJ; Fong Y. "Selective infection and cytolysis of human head and neck squamous cell carcinoma with sparing of normal mucosa by a cytotoxic herpes simplex virus type 1 (G207)." Human gene therapy. 1999; 10(10):1599-606.

Kooby DA; Carew JF; Halterman MW; Mack JE; Bertino JR; Blumgart LH; Federoff HJ; Fong Y. "Oncolytic viral therapy for human colorectal cancer and liver metastases using a multi-mutated herpes simplex virus type-1 (G207)." FASEB journal : official publication of the Federation of American Societies for Experimental Biology.. 1999; 13(11):1325-34.

Halterman MW; Miller CC; Federoff HJ. "Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53." The Journal of neuroscience : the official journal of the Society for Neuroscience.. 1999; 19(16):6818-24.

Halterman MW; Federoff HJ. "HIF-1alpha and p53 promote hypoxia-induced delayed neuronal death in models of CNS ischemia." Experimental neurology.. 1999; 159(1):65-72.

D'Angelica M; Tung C; Allen P; Halterman M; Delman K; Delohery T; Klimstra D; Brownlee M; Federoff H; Fong Y. "Herpes simplex virus (HSV)-mediated ICAM-1 gene transfer abrogates tumorigenicity and induces anti-tumor immunity." Molecular medicine (Cambridge, Mass.). 1999; 5(9):606-16.

Van de Water TR; Staecker H; Halterman MW; Federoff HJ. "Gene therapy in the inner ear. Mechanisms and clinical implications." Annals of the New York Academy of Sciences.. 1999; 884():345-60.

Brooks AI; Halterman MW; Chadwick CA; Davidson BL; Haak-Frendscho M; Radel C; Porter C; Federoff HJ. "Reproducible and efficient murine CNS gene delivery using a microprocessor-controlled injector." Journal of neuroscience methods.. 1998; 80(2):137-47.

Parry S; Holder J; Halterman MW; Weitzman MD; Davis AR; Federoff H; Strauss JF. "Transduction of human trophoblastic cells by replication-deficient recombinant viral vectors. Promoting cellular differentiation affects virus entry." The American journal of pathology.. 1998; 152(6):1521-9.

Carew JF; Federoff H; Halterman M; Kraus DH; Savage H; Sacks PG; Schantz SP; Shah JP; Fong Y. "Efficient gene transfer to human squamous cell carcinomas by the herpes simplex virus type 1 amplicon vector." American journal of surgery.. 1998; 176(5):404-8.

Federoff HJ; Halterman MW; Brooks AI. "Use of the herpes amplicon system as a vehicle for somatic gene transfer." Advanced drug delivery reviews. 1997; 27(1):29-39.

Patents

60/442,030 “Production and limited toxicity of Herpesvirus amplicon particles for gene delivery” January 23, 2003

61/391,457 "An Improved Method for the Study of Apoptosis-Related Genes Using 9-TB Regulated Expression from the TET-On System", patent pending.

61/250,281 "Methods of Treatment and Screening Assays for HIF-1-Alpha Regulation", patent pending.

61/466,906 "Crowdsourcing Medical Expertise", medical software application facilitating collaborative decision making and medical education at the point of care, patent pending.