Contact Us

Center for Translational Neuromedicine
University of Rochester
Box 645
601 Elmwood Ave.
Rochester, NY 14642

MRBX 1-11201
585-273-2717

Stefanie Fingler
Administrator

The Goldman Lab Genomics Database

To view and compare gene lists or search for a gene, please visit our genomics database.

New Approaches for Treating Neurological Diseases

The Center for Translational Neuromedicine focuses on the development of new approaches for treating neurological diseases, primarily using cell and gene therapy. Our emphasis is on using these technologies to mobilize endogenous stem and progenitor cells of the adult brain and spinal cord, as a means of structural repair. In addition, stem cell isolation and genomics analysis, as well as advanced imaging and transplant strategies are also pursued, both for biological assessment and therapeutic modeling. Our disease targets are those attributable to dysfunction or loss of single cell types; for instance, demyelinating disease is studied as a potential target for oligodendrocyte progenitor cell delivery, while Huntington’s Disease is studied as a potential beneficiary of medium spiny neuronal replacement from endogenous stem cells. Conversely, gliomas and gliomagenesis are studied from the standpoint of dysregulated signaling by endogenous glial progenitors. The principal groups in the Center include Dr. Goldman’s, whose division focuses on neural stem and glial progenitor biology, and Dr. Nedergaard’s, whose division focuses on astrocytic physiology and pathology, as well as on cerebral blood flow and its glial regulation.

Goldman Lab (Division of Cell & Gene Therapy)

Focus on cell replacement, tumorigenesis, and myelin disease

Nedergaard Lab (Division of Glial Therapeutics)

Focus on stroke and traumatic brain and spinal cord injury