2013 V Foundation Translational Award

The James P. Wilmot Cancer Center is able to put forward one qualified individual to the V Foundation for the submission of a cancer research project that brings together pre-clinical and clinical investigators.  Please see the announcement below for the details regarding this invitation. Anyone interested in applying should forward an abstract of the proposed project along with your CV to Brian Martin (Brian_Martin@URMC.Rochester.edu). Deadline for this pre-application is Monday, March 25th. The selected individual will be notified by Thursday, March 28th. Selection will be made by a subcommittee of the JPWCC Research Advisory Committee

Full Announcement

On behalf of the  Board of Directors of The V Foundation for Cancer Research, I would like to invite  you to submit  a grant  proposal  for cancer research project that  brings  together pre-clinical and clinical investigators. This  work must  not be currently funded  by other mechanisms external to your cancer center.  Translational research uses  knowledge  of human  biology to develop  and test  the  feasibility  of cancer-relevant interventions in humans  and/or determines the  biological  basis for observations made in individuals with cancer or in populations at risk for cancer.

Translational projects are permitted to move not only in the  forward  direction, toward  clinical trials  and studies in areas  of prevention, early detection, treatment, development of biomarkers, and population science, but  also in the  reverse direction, using human  biospecimens, often  from clinical  trials, to study  new phenomena, to optimize previous findings, or to develop new hypotheses based  on results from humans. Preference will be given to studies that  develop  and validate novel agents, strategies and biomarkers for personalized management of cancer.

At least one specific  aim of the  proposed project  must  address one of these human  endpoints. Experiments using cell lines or xenografts/tumor grafts  may be important to the  translational studies proposed and are encouraged, but are not sufficient to meet  the  human  endpoint requirement.

The Translational Grant  is a $6oo,ooo award  paid in $2oo,ooo installments over a three-year period. A maximum  of ten  percent of the  grant  may be used annually  to offset the  indirect costs  of the project. The project  team  must  have a minimum  of two scientists from the  same  facility, and the  team must  possess basic and clinical  research expertise.

The V Foundation is a charitable organization dedicated to saving  lives by helping  to find cures  for cancer. Founded  in 1993 by ESPN and award-winning coach  and commentator Jim Valvano, The V Foundation has raised  more than  $120 million in over 500 research and awareness grants  in 39 states and the District of Columbia.

Guidelines for the application

Proposals should consist of one (1) PDF file and include the following information in the order listed:

•  Application Cover sheet from 

•  Director's letter of recommendation.

•  A response of not more than 10 pages (references may be in addition) describing the proposed research, including specific aims, hypothesis, background, significance, and proposed methods. Please indicate likely deliverables with regard to translation from the laboratory to the clinic and from the clinic to the laboratory.

•  Provide for each investigator a list of his/her current funding.

•  Percentage of effort each investigator will contribute to project.

•  Budget for project (NIH format).   Please include the cost for one investigator to travel to a scientific meeting to present findings.

•  Bio sketch for all project team members (NIH format).

•  Short description (maximum of one page) of project in lay terms.

•  If animals are to be used in this research project, please provide rationale and a statement that they will be used in accordance with methods reviewed and approved by IACUC.

Responses are due no later than May 9, 2013 by 5:00pm Eastern time

 

NIH Funding Acknowledgement ** Important ** All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH FUNDING ACKNOWLEDGEMENT and must comply with the NIH Public Access Policy.