Center for Genomic Studies on Mental Disorders (U24)

The National Institute of Mental Health (NIMH) seeks Resource-Related Cooperative Agreement (U24) applications to continue, enhance, and enrich research resources in the NIMH Human Genetics Initiative for free and open sharing with the scientific community. The long-term objective of data sharing and research resource enrichment under this FOA is to accelerate gene discovery in mental disorders. 

It is expected that the Center will be comprised of a team of investigators with expertise in molecular biology, cell culture, computer and information sciences, statistical genetics, and psychiatric genetics. It is also expected that this effort will involve activities at multiple institutions that are strategically and functionally coordinated, such that the Center will function as a single, national resource.

A critical feature of the Center will be the banking of primary cultures of source cells for the derivation of induced pluripotent stem cells (iPSCs), as well as the banking of established iPSCs by investigators. Furthermore, the development and maintenance of a genomic cyber infrastructure is required. Such an infrastructure will represent the coordinated aggregate of software, hardware, and other technologies, as well as the necessary staff expertise required to support current and future discoveries in the genetics of mental disorders. This cyber infrastructure will integrate relevant and often disparate genetic and genomic resources to provide a useful, usable, and enabling framework for human genetic research and gene discovery in mental disorders that will be characterized by broad access.

This is a limited submission opportunity; the University may submit only one (1) grant application. Interested faculty at the Medical Center must an abstract, CV, and budget to Dean Puzas (Catherine_muzytchuk@urmc.rochester.edu) by June 12th. Please use the words “Genomic Studies” in the subject line.

The Deans will forward their ranked nominations to Mary Ann Davis in the Provost’s Office by June 19th. On June 25th, the Provost will announce which application will move forward to the NMIH.

The complete program announcement can found here. The optional letter of intent is due July 1st. The deadline for receipt of full applications is August 1st.

It is important to remember that ORPA must receive electronic proposals five (5) business days prior to the sponsor’s deadline along with a completed and signed University sign-off form.

 

NIH Funding Acknowledgement ** Important ** All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH FUNDING ACKNOWLEDGEMENT and must comply with the NIH Public Access Policy.