Molecular Atlas of Lung Development (NIH/NHLBI)

The overall goal of this program is to build an open-access reference resource by creating a comprehensive molecular atlas of the late-stage developing lung (human and mouse) with data and reagents available to the research community. The atlas will integrate gene and protein expression profiles, transcriptome, epigenome, and other molecular characterizations with high-resolution anatomical information to provide molecular profiles of functionally or anatomically defined cell types in the developing lung.

The Molecular Atlas of Lung Development Program (LungMAP) will be supported and governed by Cooperative Agreements of one Human Tissue Core (HTC), up to four Research Centers (RC), and one Data Coordinating Center (DCC), funded through FOA RFA-HL-007, RFA-HL-14-008, and RFA-HL-14-009, respectively.

Applicants are strongly encouraged to read the three FOAs for the LungMAP to better understand the overall structure and function of the entire program.

Human Tissue Core (HTC)(U01)

The NHLBI invites cooperative agreement (U01) applications to serve as the Human Tissue Core (HTC) for the Molecular Atlas of Lung Development Program (LungMAP). The HTC will identify and manage tissue source sites to collect, process, deposit, and distribute human lung samples to the Research Centers (RCs).

The complete program solicitation can be found here.  

Link: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-14-007.html

Research Center (RC) (U01)

The NHLBI invites cooperative agreement (U01) applications to serve as the Research Centers (RCs) for the Molecular Atlas of Lung Development Program (LungMAP). The purpose of the LungMAP RCs will be to focus on generating the molecular anatomy data of the developing lung, both mouse and human.

The complete program solicitation can be found here. http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-14-008.html.

Data Coordinating Center (DCC) (U01)

The NHLBI invites cooperative agreement (U01) applications to serve as the Data Coordinating Center (DCC) for the Molecular Atlas of Lung Development Program (LungMAP). The DCC will perform data collection, integration, and analysis; develop and maintain the LungMAP database and website; and coordinate research activities of the Human Tissue Core (HTC) and the Research Centers (RCs).

The complete program solicitation can be found here.

Link: http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-14-009.html

This is a limited submission opportunity. Applications for the HTC, RC, and DCC may be from the same institution if they have different PD(s)/PI(s).

Interested faculty at the Medical Center must submit an abstract, CV, and budget to Dean Puzas via Catherine Muzytchuk (Catherine_muzytchuk@urmc.rochester.edu), using the words “LungMAP” in the subject line, with the specific RFA noted. The deadline for submission to the Deans is March 29, 2013. The Deans will decide which submissions will go forward on April 8, 2013.

The optional Letter of Intent is due May 19, 2013. The full proposal is due June 19, 2013. It is important to remember that ORPA must receive electronic proposals five (5) business days prior to the sponsor’s deadline, along with a completed and signed University sign-off form.

 

 

NIH Funding Acknowledgement ** Important ** All publications resulting from the utilization of CTSI resources are required to credit the CTSI grant by including the NIH FUNDING ACKNOWLEDGEMENT and must comply with the NIH Public Access Policy.