The major groups of microorganisms causing oral disease are reviewed
with emphasis on basic biology, genetics, physiology, and pathogenic
mechanisms.
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ORB 501-504. Dental Research Seminar
The purpose of this series is to provide experience to participants
in preparing, organizing, and presenting material to a critical
audience. The fall semesters are devoted to a systematic review
of recent significant research developments in one of the basic
sciences fundamental to Oral Biology. In the spring semesters the
students report on original research. Required of all graduate
students in oral biology and open to other graduate students and
dentists.
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ORB
579. Saliva and Salivary Glands
This course gives students an understanding of the fundamental biology
of the salivary glands. The regulation of salivary gland physiology
is discussed, as is the structure/function relationship of salivary
proteins and lipids. The molecular basis of salivary gland gene
expression is explored. The etiology, pathogenesis, and consequences
of salivary gland diseases are also discussed.
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ORB 580. Fundamentals of Dental Caries
This course presents the latest developments in many aspects of dental
caries, from the most fundamental basic science to clinical applications.
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IND 501. Ethics in Research
Ethics and Professional Integrity aims to bring to light some of
the salient issues related to ethics and responsible conduct in
clinical and basic science biomedical research arenas. The course
meets weekly for 90 minutes for 10 weeks. A broad range of topics
is covered, including the University of Rochester policy and procedures
regarding human and animal experimentation, intellectual property,
as well as scientific misconduct. The course emphasizes experiential
learning in small group format, and case studies are used to facilitate
active discussion and interaction. In addition, the course features
a series of "survival skills" presentations aimed at
helping students advance in their career paths with integrity and
with the highest of ethical standards.
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Other courses administered by the Center of Oral Biology which may
be chosen as part of the program of study
ORB 414. Mechanisms of Microbial Pathogenesis
The molecular mechanisms by which bacteria cause disease are examined.
The emphasis is on understanding how bacteria colonize the host,
evade host immune defenses, and cause damage to the host, as well
as understanding the regulation of synthesis, structure, function,
and mode of action of bacterial toxins.
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ORB 556. Biology of the Periodontium
Stressing the biological behavior of the periodontium, the course
reviews the fundamentals as well as the latest developments in
periodontal research. Topics covered are the development, morphology,
and physiology of the periodontal tissues, the epidemiology, etiology
and histopathology of periodontal diseases, plus current concepts
regarding mechanisms of periodontal tissue destruction and repair.
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ORB 558. Craniofacial Growth and Development
This series covers the prenatal embryogenesis and postnatal growth
and development of the craniofacial complex. Mechanisms of growth
control, the development of occlusion, and methods of study and
timing are presented. Clinical implications for normal and abnormal
facial development are discussed.
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ORB 563. Pharmacology and Therapeutics
Pharmacotherapeutics of drugs most often used in dentistry are reviewed
with emphasis on critical analysis of the related literature and
current directions in pharmacological research.
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ORB 570. Introduction to Dental Epidemiology and Research Design
Students are introduced to the fundamentals of epidemiology. Emphasis
is placed on the natural history of common dental diseases.
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ORB 593. Complex Carbohydrates
The synthesis, structure, and function of complex carbohydrates is
considered with emphasis on recognition phenomena.
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Some courses administered by other centers and departments that
are frequently chosen by students
IND 408. Biochemistry
MBI 473. Immunology
STT 212. Applied Statistics for the Biological and Physical Sciences
LAM 402. Laboratory Animal Experiments
For more information: OralBiology@urmc.rochester.edu
