Research

  • Cell Biology

    Cell Biology

    Microbes and viruses interact with host cells to induce alterations in cellular phenotype and function, thereby subverting host cell metabolism to meet their own needs. In addition, many microbes and viruses exert effects on the host immune response, so as to evade host immune control. Knowledge of the interplay between infectious pathogens and their host cells is therefore important, in order to identify potential new targets for drug therapy and as a basis for understanding microbial pathogenesis. Research focuses on various aspects of mammalian and amphibian cell biology including, cell to cell interactions, cell cycle control, intracellular signaling, differentiation and subcellular organelles.

    Active Research Laboratories

    • Zhu Lab Host-Virus Interactions, Particularly for HIV and Herpes Viruses
  • DNA Replication, Repair & Recombination

    DNA Replication, Repair & Recombination

    The fundamental processes DNA undergoes during the cell cycle to both maintain the integrity of the DNA and create genetic diversity.

    Active Research Laboratories

  • Gene Regulation

    Gene Regulation

    Processes that cells and viruses use to turn the information in genes into gene products.

    Active Research Laboratories

    • Bi Lab Chromatin Regulation of Gene Expression in Eukaryotes
    • Bohmann Lab JNK, Fos, Foxo and Nrf2 Dependent Signaling and Gene Regulation in Oxidative Stress Response and Aging
    • Bulger Lab Chromatin Domains and Enhancer Activation
    • Hayes Lab Chromatin Structure
    • William A. Bernhard Memorial Lab Physics & Chemistry of DNA Damage Produced by Ionizing Radiation
    • Zhao Lab Cell Proliferation and Mammalian Cells
  • Molecular Mechanisms in Cell Function and Disease

    Molecular Mechanisms in Cell Function and Disease

    Investigate the molecular mechanisms that govern cell function and are responsible for pathological processes.

    Active Research Laboratories

    • Brookes Lab Cardiac Ischemia-Reperfusion (IR) Injury and Cardioprotection
    • Goldfarb Lab Nuclear Transport and Autophagy
    • Land Lab Cooperation of Oncogenic Mutations in the Control of Malignancy
    • Maquat Lab Normal & Disease-Associated RNA Decay
    • Munger Lab Mechanisms of Pathogenic Metabolic Manipulation
    • Smith Lab Messenger RNA Expression & Processing
    • Xin Li Lab Reproductive and RNA Biology
    • Zhao Lab Cell Proliferation and Mammalian Cells
  • Protein Structure & Function

    Protein Structure & Function

    Structure and function of proteins from primary to quaternary structures.

    Active Research Laboratories

  • RNA Structure & Processing

    RNA Structure & Processing

    Generation of a mature mRNA (for protein genes) or a functional tRNA or rRNA from the primary transcript.

    Active Research Laboratories

    • Butler Lab Regulation of mRNA Expression in the Nucleus of Eukaryotic Cells
    • Ermolenko Lab Structural Dynamics of Translation
    • Kielkopf Lab Pre-mRNA Splicing for Treatment of Human Disease
    • Maquat Lab Normal & Disease-Associated RNA Decay
    • Mathews Lab Computational Biology and Bioinformatics
    • Phizicky Lab tRNA Biogenesis, Function & Quality Control
    • Smith Lab Messenger RNA Expression & Processing
    • Turner Lab Forces Directing Nucleic Acid Chemistry, with Particular Emphasis on RNA Folding
    • Wedekind Lab Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
    • Xin Li Lab Reproductive and RNA Biology
    • Yu Lab Functions & Mechanisms of RNA Modifications
  • Signal Transduction

    Signal Transduction

    Processes by which an extracellular signaling molecule activates a membrane receptor that in turn alters intracellular molecules creating a response.

    Active Research Laboratories

    • Bohmann Lab JNK, Fos, Foxo and Nrf2 Dependent Signaling and Gene Regulation in Oxidative Stress Response and Aging
    • Dickerson Lab CGRP Signal Transduction
    • Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
    • Grossfield Lab Computer Modeling to Understand Structure and Thermodynamics of Biological Molecules
    • Land Lab Cooperation of Oncogenic Mutations in the Control of Malignancy
    • Maines Lab Heme Oxygenase, Biliverdin Reductase & Cell Signalling
    • Munger Lab Mechanisms of Pathogenic Metabolic Manipulation
    • Smrcka Lab Molecular Mechanisms of Signal Transduction
    • Zhao Lab Cell Proliferation and Mammalian Cells

Apply Now

For more information and details on how to apply please visit the Office for Graduate Education and Postdoctoral Affairs.