Research

  • Cellular and Membrane Biophysics

    Cellular and Membrane Biophysics

    Study of biological membranes using physical, computational, mathematical, and biophysical methods.

    Active Research Laboratories

  • Genomics

    Genomics

    The structure, function, evolution, and mapping of genomes.

    Active Research Laboratories

    • Bernhard Lab Physics & Chemistry of DNA Damage Produced by Ionizing Radiation
    • Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
    • Maquat Lab Normal & Disease-Associated RNA Decay
    • Miller (Benjamin) Lab Molecular Recognition & Biosensing
    • Phizicky Lab tRNA Biogenesis, Function & Quality Control
    • Turner Lab The Forces Directing Nucleic Acid Chemistry, with Particular Emphasis on RNA Folding
  • Macromolecular Folding & Design

    Macromolecular Folding & Design

    Understanding polypeptide folding function and characteristics.

    Active Research Laboratories

    • Bren Lab Bioinorganic and Biophysical Chemistry
    • Mathews Lab Computational Biology and Bioinformatics
    • Turner Lab The Forces Directing Nucleic Acid Chemistry, with Particular Emphasis on RNA Folding
  • Membrane Proteins

    Membrane Proteins

    Protein molecules that are attached to, or associated with the membrane of a cell or an organelle.

    Active Research Laboratories

    • Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
    • Grossfield Lab Use of Computer Modeling to Understand the Structure and Thermodynamics of Biological Molecules
    • Novotny Lab Nano-Optics Group
  • Nucleic Acid Structure & Function

    Nucleic Acid Structure & Function

    Study of the structure and function of DNA and RNA.

    Active Research Laboratories

    • Bernhard Lab Physics & Chemistry of DNA Damage Produced by Ionizing Radiation
    • Hayes Lab Chromatin Structure
    • Kielkopf Lab Study of pre-RNA Transcripts in Order to Treat Human Genetic Diseases
    • Krugh Lab Structure Determination of Nucleic Acids by NMR
    • Lawrence Lab DNA-Damage Induced Mutagenesis
    • Maquat Lab Normal & Disease-Associated RNA Decay
    • Mathews Lab Computational Biology and Bioinformatics
    • Miller (Benjamin) Lab Molecular Recognition & Biosensing
    • Phizicky Lab tRNA Biogenesis, Function & Quality Control
    • Turner Lab The Forces Directing Nucleic Acid Chemistry, with Particular Emphasis on RNA Folding
    • Wedekind Lab Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics
  • Protein Structure & Function

    Protein Structure & Function

    Structure and function of proteins from primary to quaternary structures.

    Active Research Laboratories

    • Bren Lab Bioinorganic and Biophysical Chemistry
    • Dumont Lab Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology
    • Hayes Lab Chromatin Structure
    • Kielkopf Lab Study of pre-RNA Transcripts in Order to Treat Human Genetic Diseases
    • Maquat Lab Normal & Disease-Associated RNA Decay
    • Miller (Benjamin) Lab Molecular Recognition & Biosensing
    • Novotny Lab Nano-Optics Group
    • Phizicky Lab tRNA Biogenesis, Function & Quality Control
    • Stern Lab Computational Modeling of Proteins, Nucleic Acids, and Their Interactions with Small Molecules
    • Wedekind Lab Development of New HIV/AIDS Drugs, Antibiotics, & RNA-based Therapeutics

Apply Now

For more information and details on how to apply please visit the Office for Graduate Education and Postdoctoral Affairs.

Research Techniques

In addition to research areas many of our labs employ the following research techniques:

  • Spectroscopy (e.g., NMR, EPR, Fluorescence)
  • X-ray Crystallography
  • Thermodynamic and Kinetic Measurements
  • Computational Methods
  • Molecular Biology
  • Electrophysiology

Centers

Interactions in Biophysics, Structural & Computational Biology are fostered and strengthened by a host of interdisciplinary research centers.