Sixth Year (Ph.D. Program in Pathology)

 

Andrew Campbell

As a graduate student at the University of Rochester, I plan to pursue hypothesis driven research that will add to the current understanding of human health and disease.  In my previous work, I was involved in studying the interaction of the immune system and leukemia cells following bone marrow transplantation.  Currently I am studying the developmental fate of glial restricted progenitor cell in order to determine its potential as a therapeutic for nervous system injury and disease.

Hometown: Rochester, NY
M.S., Forensic Biology, SUNY at Albany

Mentor: Margot Mayer-Proschel

Andrew Campbell

Hsing-Yu Chen (Warner)

Resistance to chemo-therapeutics is way too common and it is a priority to overcome in cancer treatment. Cancer stem cells have been identified as one of main causes of chemotherapy resistance. My research is concentrating on understanding the mechanism that tumor cells utilize to escape the current breast cancer therapy.

Hometown: Taipei, Taiwan
M.S., Biology, New York University

Mentor: Mark Noble

Hsing-Yu Chen

Tulin Dadali

Nicotinamide adenine dinucleotide (NAD+) is known to be critical in cellular responses, redox reactions, signaling, DNA repair as well as paracrine and autocrine functions. It is known that extracellular metabolites, such as ATP, are able to contribute to immune responses, however the role of extracellular NAD in immune function is still elusive. My primary research focuses on manipulating extracellular NAD levels to modulate cell trafficking, inflammation, and autoimmunity.

Hometown: Rochester, NY
B.S., Biotechnology, Rochester Institute of Technology

Mentor: Frances Lund

Tulin Dadali

Tzu-Chieh Ho (Kate)

My current research focuses on characterizing leukemia stem cells in acute myeloid leukemia after drug therapy.

Hometown: Taipei, Taiwan
M.S., Biochemistry, National Taiwan University

Mentors: Michael Becker and Craig Jordan

Tzu-Chieh (Kate) Ho

Hsi-Min Hsiao (Jim)

I am interested in at looking at the effects of anti-Inflammatory and pro-resolving lipid mediator resolvin D1 on cigarette smoke-induced lung inflammation In vitro and In vivo.

Hometown: Taipei, Taiwan
M.S., Biochemistry, National Cheng Kung University

Mentors: Patricia Sime and Richard Phipps

Hsi-Min (Jim) Hsiao

Yawen Ju

My current research is to investigate the formation of osteoclasts, which is a key point to understanding the mechanism of errosive arthritics.

Hometown: Nanchang, Jiangxi, China
B.S., Pharmacy, China Pharmaceutical University

Mentor: Edward Schwarz

Yawen Ju

I-Hsin Kuo (Fiona)

My research interests involve studying epithelial tight junction defects in atopic dermatitis, the most common inflammatory skin disease in humans. I am currently characterizing the effect of innate immune receptors on regulation of skin barrier function.

Hometown: Taipei, Taiwan
M.S., Toxicology, National Taiwan University

Mentor: Lisa Beck

I-Hsin (Fiona) Kuo

Sara Montgomery

My research focus relates to elucidating the stage-specific impact of TNF-alpha receptor signaling in Alzheimer’s disease.  I am utilizing a mouse model of the disease completely devoid of cognate TNF-alpha receptor expression, and vector vector-based RNAi technology to selectively abrogate receptor expression at specific stages of the disease process in vivo.

Hometown: Locke, NY
B.S., Biotechnology, Rochester Institute of Technology

Mentor: William Bowers

Sara Montgomery

Michael Moses

Prostate cancer is the most common non-cutaneous cancer of the American male population, therefore, identifying new small molecules and therapeutic targets are active areas of research. Using a unique human prostate cancer progression model, I am examining the stage-specific sensitivity and mechanism of action of epigallocatechin gallate (EGCG), the most abundant catechin in green tea.

Hometown: Geneva, NY
B.S., Biomolecular Science, Clarkson University

Mentor: Thomas Gasiewicz

Michael Moses

Shanshan Shi

My research interest is the role of TGFb1 on tendon healing.

Hometown: Beijing, China
B.A., Genetics, Ohio Weslyan University

Mentor: Regis O'Keefe

Shanshan Shi

Julianne Smith

My research interests lie in stem cell and regenerative medicine. I am interested in microenvironmental effects on stem cells and/or cancer cells. Specifically, I enjoy studying hematopoiesis and other components of the bone marrow. I hope my work will be applicable to disease understanding and treatment.

Hometown: Cleveland, OH
B.S., Microbiology & Immunology, University of Rochester

Mentor: Laura Calvi

Julianne Smith