Optical Micro-machining using Femtosecond Lasers

Project Overview

Femto Micro-machiningIRIS stands for Intratissue Refractive Index Shaping.  It is a process invented at the University of Rochester by a team of scientists under the leadership of Dr's. Krystel Huxlin and Wayne Knox who demonstrated that it was possible to use a low-energy, high-repetition rate femtosecond laser to alter the refractive index of transparent, living tissues (such as the cornea and lens) without causing massive amounts of tissue damage or inducing a wound healing and scarring response.

Our long-term goal with this research is to develop the use of femtosecond micromachining as a non-damaging method of customizing the refractive correction in a human eye, be it in the cornea, lens or implanted IOLs. Current experiments are first testing and developing this technology in animal models, with specific projects including:

(1) assessing the durability of inscribed femto-IRIS patterns in a living cornea over time,

(2) assessing the biological reaction and especially, the presence or absence of a corneal wound healing reaction to an inscribed femto-IRIS pattern in a living cornea over time,

(3) assessing the wavefront aberration changes induced by a spherical or cylindrical IRIS pattern over time.

Optical Micro-machiining using Femtosecond Lasers

Contact

Krystel Huxlin, Ph.D.
University of Rochester
School of Medicine and Dentistry 601 Elmwood Ave., Box 659
Rochester, NY 14642
+1-585-273-2609
huxlin@cvs.rochester.edu

Collaborators

Holly Hindman, M.D.

Scott MacRae, M.D.

Past Collaborator

Jens Bühren, M.D.