Skin-Derived Fibroblast Culture

Background: Fibroblasts provide an alternative cell line to myoblasts for certain experiments such as detailed genotyping and methylation studies. In contrast to myoblasts, they are easier to grow in abundant quantities. All fibroblasts used in the Fields Center are derived from skin sampled by punch biopsy at the distal ulnar aspect of the forearm about 3 cm proximal to the wrist. Samples are collected from indivudals with FSHD (FSH dystrophy) and normal controls.




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