B5. Androgen Receptor in SBMA-Neuron diseases / Dermatology

  1. Simerly RB, Chang C, Muramatsu M, and Swanson LW "The distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study." Journal of Comparative Neurology, (1990):294(1), 76-95. PMID: 2324335.

  2. Lustig RH, Hua P, Smith LS, Wang C, and Chang C "An in vitro model for the effects of androgen on neurons employing androgen receptor-transfected PC12 cells." Mol. Cel. Neuro Sciences. (1994):5(6), 587-96. PMID: 7704433.

  3. Obana N, Chang C, and Uno H "Inhibition of hair growth by testosterone in the presence of dermal papilla cells from the frontal bald scalp of the postpubertal stumptailed macaque." Endocrinology, (1997):138(1), 356-1. PMID: 8977424.

  4. Schirar A, Chang C, and Rousseau JP "Localization of androgen receptor in nitric oxide synthase- and vasoactive intestinal peptide-containing neurons of the major pelvic ganglion innervating the rat penis." Journal of Neuroendocrinology (1997):9(2), 141-50. PMID: 9041368.

  5. Young WJ, and Chang C "Ontogeny and autoregulation of androgen receptor mRNA expression in the nervous system." Endocrine (1998):9(1), 79-88. PMID: 9798734.

  6. Pan H-J, Wilding G, Uno H, Inui S, Goldsmith L, Messing E, and Chang C "Evaluation of RU58841 as an antiandrogen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of Stumptailed Macaques." Endocrine (1998):9(1), 39-43. PMID: 9798729.

  7. Hsiao P, Lin D, Nakao K, and Chang C "The linkage of the Kennedy's neuron disease to ARA24, the first identified androgen receptor poly-glutamine region-associated coactivator." J. Biol. Chem. (1999): 274(29):20229-34. PMID: 10400640.

  8. Pan H, Uno H, Obana N, and Chang C "The roles of testosterone in the growth of keratinocytes through bald frontal dermal papilla cells." Endocrine (1999): 138(1):356-61. PMID: 8977424.

  9. Inui S, Itami S, Pan H, and Chang C "Lack of androgen receptor transcriptional activity in human keratinocytes." J. Dermatological Science (2000): 23(2):87-92. PMID: 10808125.

  10. Inui S, Nakajima T, Fukuzato Y, Fujimoto N, Chang C, Yoshikawa K, Itami S "Potential anti-androgenic activity of roxithromycin in skin. "J Dermatol Sci. (2001): 27(2):147-51. PMID: 11532379.

  11. Itami S. Inui S, Uno H, Pan H, Chang E, Takayasu S, Ye F, Imamura K, Seki T, Ideta R, Aoki H, Adachi K, Price V, Kurata S, Collins L, Heinlein C and Chang C "Androgens in Dermatology: Hair Loss, Acne, and Other Diseases." pp 411-476 in Androgens and Androgen Receptor: Mechanisms, Functions and Clinical Application. (Chang C ed). (2002):Kluwer, USA.

  12. Yang Z, Chang YJ, Yu IC, Miyamoto H, Wu CC, Yeh S, Merry DE, Sobue G, Chen LM and Chang C "ASC-J9 ameliorates spinal and bulbar muscular atrophyphenotype via degradation of androgen receptor" Nature Medicine, (2007):13(3): 348 - 53. PMID:17334372. This Nature Medicine Paper got over 50-newspapers reporting and 2-TV-stations interviewing. Click the following links to see those reports from English newspaper, Chinese newspaper and Taiwanese newspaper.

  13. Lai JJ, Lai KP, Chuang KH, Chang P, Yu IC, Wen-Jye Lin, and Chang C "Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-α expression" JCI (2009). PMID

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