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Progenitor cell-based myelination of congenitally dysmyelinated brain

Human progenitor cells (blue, top figures; red, bottom figures) myelinate fibers of the corpus callosum in a congenitally dysmyelinated mouse, the shiverer (myelin basic protein: red, top; green, bottom).

**Shiverer (Windrem *et al.* 2004)**

Funded by NMSS RG 2898-C-3

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Steven Goldman

Abdel Benraiss Min Guo Gang Lu Fraser Sim Neeta Roy Su Wang Martha Windrem

Projects

Human Oligodendrocyte Progenitor Molecular Biology Human neural stem and progenitor cell genomics and differential signaling Tumor stem & progenitor cells of the human CNS Induced neurogenesis in neurodegenerative Disease Progenitor cell-based myelination of congenitally dysmyelinated brain Relationship between angiogenesis & neurogenesis in the adult Canary Regulation of astrocytosis from endogenous progenitors Neural phenotypic direction and therapeutic use of human ES cells Human Motor Neuron induction and targeting

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Last updated: 9/12/2007