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IdStudy TitleThe Question the Study Seeks to Answer
10003PREMIUM Trial Prospective Randomized investigation to Evaluate incidence of headache reduction in subjects with Migraine and PFO Using the AMPLATZER PFO Occluder compared to Medical ManagementHow does an occluder device to close a PFO compare to current standard treatment of care in reducing further episodes of migraine. Current standard of care treatment is medicine.
10069Finding the best corticosteroid for Duchenne muscular dystrophy (FOR DMD)Which corticosteroid increases muscle strength the most and causes the fewest side effects in boys with Duchenne muscular dystrophy?
10122Spinal Muscular Atrophy (SMA) studyWhat are the most informative tests that should be included in future spinal muscular atrophy (SMA) studies, when should treatments be given to SMA patients and what happens to the SMN protein level as children grow?
10125CREST-E HD Study: Creatine Safety, Tolerability and Efficacy in Huntington’s DiseaseCan creatine slow the functional decline that occurs in persons with early Huntington’s Disease?
10127Equivalence of Generic and Brand Name Drugs in Epilepsy (EQUIGEN Single-Dose Study)Will generic versions and brand name versions of lamotrigine have the same effect on people with epilepsy?
10131Determining Risks for Progression in Multiple Sclerosis * Is collecting information from people with Multiple Sclerosis (MS) over time feasible and is the information collected useful in helping to determine possible risk factors for disease progression?
10143Research study of C. difficile vaccine for people at risk for C. difficile infection.Will the study vaccine for C. difficile infection be safe and produce an immune response?
10232National Registry of Myotonic Dystrophy (DM) and Facioscapulohumeral Muscular Dystrophy (FSHD)The goals of the National Registry are to connect patients with researchers and to study the symptoms and progression of DM and FSHD.