Imaging Sciences

Preclinical Evaluation PDT

Representative Publications

Preclinical Evaluation of PDTT.M. Baran, B.R. Giesselman, R. Hu, M.A. Biel, and T.H. Foster. Factors influencing tumor response to photodynamic therapy sensitized by intratumor administration of methylene blue. Lasers Surg. Med. 42, 728-735 (2010) [Erratum: Lasers Surg. Med. 43, 183 (2011)]. [Medline]

T.H. Foster, B.R. Giesselman, R. Hu, M.E. Kenney, and S. Mitra. Intratumor administration of the photosensitizer Pc 4 affords photodynamic therapy efficacy and selectivity at short drug-light intervals. Transl. Oncol. 3, 135-141 (2010). [PDF]

J. Garrier, A. Bressenot, S. Gräfe, S. Marchal, S. Mitra, T.H. Foster, F. Guillemin, and L. Bezdetnaya. Compartmental targeting for mTHPC based photodynamic treatment in vivo: correlation of efficiency, pharmacokinetics and regional distribution of apoptosis. Int. J. Radiat. Oncol. Biol. Phys. 78, 563-571 (2010). [Medline]

S. Mitra and T.H. Foster In vivo confocal fluorescence imaging of the intratumor distribution of the photosensitizer mono-L-aspartylchlorin-e6 (NPe6). Neoplasia 10, 429-438 (2008). [Medline]


Thomas Foster
University of Rochester Medical Center
School of Medicine and Dentistry
601 Elmwood Ave, Box 648
Rochester, NY 14642