Principal Investigator

Hani A. Awad, Ph.D. University of Rochester work Box 665 601 Elmwood Ave Rochester NY 14642 office: MC 1-8543 p 585-273-5268 f 585-273-4746 Hani_Awad@urmc.rochester.edu

Recent Publications

The following list was auto-generated 1 week ago.

1. Chen T
2. Hilton MJ
3. Brown EB
4. Zuscik MJ
5. Awad HA
(2013 May 01). Engineering superficial zone features in tissue engineered cartilage. Biotechnol Bioeng. 110, 1476-86.
1. Chu JY
2. Chen T
3. Awad HA
4. Elfar J
5. Hammert WC
(2013 Apr 09). Comparison of an All-Inside Suture Technique With Traditional Pull-Out Suture and Suture Anchor Repair Techniques for Flexor Digitorum Profundus Attachment to Bone. J Hand Surg Am. In press.
1. Dhillon RS
2. Xie C
3. Tyler W
4. Calvi LM
5. Awad HA
6. Zuscik MJ
7. O'Keefe RJ
8. Schwarz EM
(2013 Mar 01). PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis. J Bone Miner Res. 28, 586-97.
1. Inzana JA
2. Maher JR
3. Takahata M
4. Schwarz EM
5. Berger AJ
6. Awad HA
(2013 Feb 22). Bone fragility beyond strength and mineral density: Raman spectroscopy predicts femoral fracture toughness in a murine model of rheumatoid arthritis. J Biomech. 46, 723-30.
1. Juneja SC
2. Schwarz EM
3. O'Keefe RJ
4. Awad HA
(2013 Jan 01). Cellular and molecular factors in flexor tendon repair and adhesions: a histological and gene expression analysis. Connect Tissue Res. 54, 218-26.
1. Takahata M
2. Maher JR
3. Juneja SC
4. Inzana J
5. Xing L
6. Schwarz EM
7. Berger AJ
8. Awad HA
(2012 Nov 01). Mechanisms of bone fragility in a mouse model of glucocorticoid-treated rheumatoid arthritis: implications for insufficiency fracture risk. Arthritis Rheum. 64, 3649-59.
1. Chen T
2. Buckley M
3. Cohen I
4. Bonassar L
5. Awad HA
(2012 May 01). Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels. Biomech Model Mechanobiol. 11, 689-702.
1. Takahata M
2. Awad HA
3. O'Keefe RJ
4. Bukata SV
5. Schwarz EM
(2012 Mar 01). Endogenous tissue engineering: PTH therapy for skeletal repair. Cell Tissue Res. 347, 545-52.
1. Farhat YM
2. Al-Maliki AA
3. Chen T
4. Juneja SC
5. Schwarz EM
6. O'Keefe RJ
7. Awad HA
(2012 Jan 01). Gene expression analysis of the pleiotropic effects of TGF-β1 in an in vitro model of flexor tendon healing. PLoS One. 7, e51411.
1. Loiselle AE
2. Frisch BJ
3. Wolenski M
4. Jacobson JA
5. Calvi LM
6. Schwarz EM
7. Awad HA
8. O'Keefe RJ
(2012 Jan 01). Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury. PLoS One. 7, e40602.
1. Takahata M
2. Schwarz EM
3. Chen T
4. O'Keefe RJ
5. Awad HA
(2012 Jan 01). Delayed short-course treatment with teriparatide (PTH(1-34)) improves femoral allograft healing by enhancing intramembranous bone formation at the graft-host junction. J Bone Miner Res. 27, 26-37.
1. Zhao L
2. Huang J
3. Zhang H
4. Wang Y
5. Matesic LE
6. Takahata M
7. Awad H
8. Chen D
9. Xing L
(2011 Oct 01). Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1. Stem Cells. 29, 1601-10.
1. Sampson ER
2. Hilton MJ
3. Tian Y
4. Chen D
5. Schwarz EM
6. Mooney RA
7. Bukata SV
8. O'Keefe RJ
9. Awad H
10. Puzas JE
11. Rosier RN
12. Zuscik MJ
(2011 Sep 21). Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis. Sci Transl Med. 3, 101ra93.
1. Papuga MO
2. Kwok E
3. You Z
4. Rubery PT
5. Dougherty PE
6. Pryhuber G
7. Beck CA
8. Hilton MJ
9. Awad HA
10. Schwarz EM
(2011 Sep 01). TNF is required for the induction but not the maintenance of compression-induced BME signals in murine tail vertebrae: limitations of anti-TNF therapy for degenerative disc disease. J Orthop Res. 29, 1367-74.
1. Maher JR
2. Takahata M
3. Awad HA
4. Berger AJ
(2011 Aug 01). Raman spectroscopy detects deterioration in biomechanical properties of bone in a glucocorticoid-treated mouse model of rheumatoid arthritis. J Biomed Opt. 16, 087012.
1. Sampson ER
2. Beck CA
3. Ketz J
4. Canary KL
5. Hilton MJ
6. Awad H
7. Schwarz EM
8. Chen D
9. O'Keefe RJ
10. Rosier RN
11. Zuscik MJ
(2011 Aug 01). Establishment of an index with increased sensitivity for assessing murine arthritis. J Orthop Res. 29, 1145-51.
1. Yazici C
2. Takahata M
3. Reynolds DG
4. Xie C
5. Samulski RJ
6. Samulski J
7. Beecham EJ
8. Gertzman AA
9. Spilker M
10. Zhang X
11. O'Keefe RJ
12. Awad HA
13. Schwarz EM
(2011 Aug 01). Self-complementary AAV2.5-BMP2-coated femoral allografts mediated superior bone healing versus live autografts in mice with equivalent biomechanics to unfractured femur. Mol Ther. 19, 1416-25.
1. Katzel EB
2. Koltz PF
3. Tierney R
4. Williams JP
5. Awad HA
6. O'keefe RJ
7. Langstein HN
(2011 Jun 01). The impact of Smad3 loss of function on TGF-β signaling and radiation-induced capsular contracture. Plast Reconstr Surg. 127, 2263-9.
1. Yee M
2. White RJ
3. Awad HA
4. Bates WA
5. McGrath-Morrow SA
6. O'Reilly MA
(2011 Jun 01). Neonatal hyperoxia causes pulmonary vascular disease and shortens life span in aging mice. Am J Pathol. 178, 2601-10.
1. Katzel EB
2. Wolenski M
3. Loiselle AE
4. Basile P
5. Flick LM
6. Langstein HN
7. Hilton MJ
8. Awad HA
9. Hammert WC
10. O'Keefe RJ
(2011 May 01). Impact of Smad3 loss of function on scarring and adhesion formation during tendon healing. J Orthop Res. 29, 684-93.
1. Zhang M
2. Ho HC
3. Sheu TJ
4. Breyer MD
5. Flick LM
6. Jonason JH
7. Awad HA
8. Schwarz EM
9. O'Keefe RJ
(2011 Apr 01). EP1(-/-) mice have enhanced osteoblast differentiation and accelerated fracture repair. J Bone Miner Res. 26, 792-802.
1. Reynolds DG
2. Takahata M
3. Lerner AL
4. O'Keefe RJ
5. Schwarz EM
6. Awad HA
(2011 Mar 01). Teriparatide therapy enhances devitalized femoral allograft osseointegration and biomechanics in a murine model. Bone. 48, 562-70.
1. Jacobson JA
2. Yanoso-Scholl L
3. Reynolds DG
4. Dadali T
5. Bradica G
6. Bukata S
7. Puzas EJ
8. Zuscik MJ
9. Rosier R
10. O'Keefe RJ
11. Schwarz EM
12. Awad HA
(2011 Feb 01). Teriparatide therapy and beta-tricalcium phosphate enhance scaffold reconstruction of mouse femoral defects. Tissue Eng Part A. 17, 389-98.
1. Yanoso-Scholl L
2. Jacobson JA
3. Bradica G
4. Lerner AL
5. O'Keefe RJ
6. Schwarz EM
7. Zuscik MJ
8. Awad HA
(2010 Dec 01). Evaluation of dense polylactic acid/beta-tricalcium phosphate scaffolds for bone tissue engineering. J Biomed Mater Res A. 95, 717-26.
1. Katzel EB
2. Koltz PF
3. Tierney R
4. Williams JP
5. Awad HA
6. O'Keefe RJ
7. Langstein HN
(2010 Nov 01). A novel animal model for studying silicone gel-related capsular contracture. Plast Reconstr Surg. 126, 1483-91.
1. Papuga MO
2. Proulx ST
3. Kwok E
4. You Z
5. Rubery PT
6. Dougherty PE
7. Hilton MJ
8. Awad HA
9. Schwarz EM
(2010 Sep 01). Chronic axial compression of the mouse tail segment induces MRI bone marrow edema changes that correlate with increased marrow vasculature and cellularity. J Orthop Res. 28, 1220-8.
1. Li D
2. Gromov K
3. Proulx ST
4. Xie C
5. Li J
6. Crane DP
7. Søballe K
8. O'Keefe RJ
9. Awad HA
10. Xing L
11. Schwarz EM
(2010 Mar 01). Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw. Ann N Y Acad Sci. 1192, 84-94.
1. Yan Y
2. Tang D
3. Chen M
4. Huang J
5. Xie R
6. Jonason JH
7. Tan X
8. Hou W
9. Reynolds D
10. Hsu W
11. Harris SE
12. Puzas JE
13. Awad H
14. O'Keefe RJ
15. Boyce BF
16. Chen D
(2009 Oct 01). Axin2 controls bone remodeling through the beta-catenin-BMP signaling pathway in adult mice. J Cell Sci. 122, 3566-78.
1. Loiselle AE
2. Bragdon GA
3. Jacobson JA
4. Hasslund S
5. Cortes ZE
6. Schwarz EM
7. Mitten DJ
8. Awad HA
9. O'Keefe RJ
(2009 Jun 01). Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression. J Orthop Res. 27, 833-40.
1. Reynolds DG
2. Shaikh S
3. Papuga MO
4. Lerner AL
5. O'Keefe RJ
6. Schwarz EM
7. Awad HA
(2009 May 01). muCT-based measurement of cortical bone graft-to-host union. J Bone Miner Res. 24, 899-907.
1. Cheng NC
2. Estes BT
3. Awad HA
4. Guilak F
(2009 Feb 01). Chondrogenic differentiation of adipose-derived adult stem cells by a porous scaffold derived from native articular cartilage extracellular matrix. Tissue Eng Part A. 15, 231-41.
1. Naik AA
2. Xie C
3. Zuscik MJ
4. Kingsley P
5. Schwarz EM
6. Awad H
7. Guldberg R
8. Drissi H
9. Puzas JE
10. Boyce B
11. Zhang X
12. O'Keefe RJ
(2009 Feb 01). Reduced COX-2 expression in aged mice is associated with impaired fracture healing. J Bone Miner Res. 24, 251-64.
1. Wu Q
2. Kim KO
3. Sampson ER
4. Chen D
5. Awad H
6. O'Brien T
7. Puzas JE
8. Drissi H
9. Schwarz EM
10. O'Keefe RJ
11. Zuscik MJ
12. Rosier RN
(2008 Oct 01). Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice. Arthritis Rheum. 58, 3132-44.
1. Yazici C
2. Yanoso L
3. Xie C
4. Reynolds DG
5. Samulski RJ
6. Samulski J
7. Yannariello-Brown J
8. Gertzman AA
9. Zhang X
10. Awad HA
11. Schwarz EM
(2008 Oct 01). The effect of surface demineralization of cortical bone allograft on the properties of recombinant adeno-associated virus coatings. Biomaterials. 29, 3882-7.
1. Tsutsumi R
2. Hock C
3. Bechtold CD
4. Proulx ST
5. Bukata SV
6. Ito H
7. Awad HA
8. Nakamura T
9. O'Keefe RJ
10. Schwarz EM
(2008 Oct 01). Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT. J Orthop Res. 26, 1340-6.
1. Dipaola CP
2. Jacobson JA
3. Awad H
4. Conrad BP
5. Rechtine GR
(2008 Aug 29). Screw orientation and plate type (variable- vs. fixed-angle) effect strength of fixation for in vitro biomechanical testing of the Synthes CSLP. Spine J. 8, 717-22.
1. Guo R
2. Yamashita M
3. Zhang Q
4. Zhou Q
5. Chen D
6. Reynolds DG
7. Awad HA
8. Yanoso L
9. Zhao L
10. Schwarz EM
11. Zhang YE
12. Boyce BF
13. Xing L
(2008 Aug 22). Ubiquitin ligase Smurf1 mediates tumor necrosis factor-induced systemic bone loss by promoting proteasomal degradation of bone morphogenetic signaling proteins. J Biol Chem. 283, 23084-92.
1. Zhang X
2. Awad HA
3. O'Keefe RJ
4. Guldberg RE
5. Schwarz EM
(2008 Aug 01). A perspective: engineering periosteum for structural bone graft healing. Clin Orthop Relat Res. 466, 1777-87.
1. Proulx ST
2. Kwok E
3. You Z
4. Papuga MO
5. Beck CA
6. Shealy DJ
7. Calvi LM
8. Ritchlin CT
9. Awad HA
10. Boyce BF
11. Xing L
12. Schwarz EM
(2008 Jul 01). Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging. Arthritis Rheum. 58, 2019-29.
1. Hasslund S
2. Jacobson JA
3. Dadali T
4. Basile P
5. Ulrich-Vinther M
6. Søballe K
7. Schwarz EM
8. O'Keefe RJ
9. Mitten DJ
10. Awad HA
(2008 Jun 01). Adhesions in a murine flexor tendon graft model: autograft versus allograft reconstruction. J Orthop Res. 26, 824-33.
1. Chen M
2. Zhu M
3. Awad H
4. Li TF
5. Sheu TJ
6. Boyce BF
7. Chen D
8. O'Keefe RJ
(2008 May 01). Inhibition of beta-catenin signaling causes defects in postnatal cartilage development. J Cell Sci. 121, 1455-65.
1. Basile P
2. Dadali T
3. Jacobson J
4. Hasslund S
5. Ulrich-Vinther M
6. Søballe K
7. Nishio Y
8. Drissi MH
9. Langstein HN
10. Mitten DJ
11. O'Keefe RJ
12. Schwarz EM
13. Awad HA
(2008 Mar 01). Freeze-dried tendon allografts as tissue-engineering scaffolds for Gdf5 gene delivery. Mol Ther. 16, 466-73.
1. Butler DL
2. Juncosa-Melvin N
3. Boivin GP
4. Galloway MT
5. Shearn JT
6. Gooch C
7. Awad H
(2008 Jan 01). Functional tissue engineering for tendon repair: A multidisciplinary strategy using mesenchymal stem cells, bioscaffolds, and mechanical stimulation. J Orthop Res. 26, 1-9.
1. Li D
2. Gromov K
3. Søballe K
4. Puzas JE
5. O'Keefe RJ
6. Awad H
7. Drissi H
8. Schwarz EM
(2008 Jan 01). Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity. J Orthop Res. 26, 96-105.
1. Proulx ST
2. Kwok E
3. You Z
4. Papuga MO
5. Beck CA
6. Shealy DJ
7. Ritchlin CT
8. Awad HA
9. Boyce BF
10. Xing L
11. Schwarz EM
(2007 Dec 01). Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography. Arthritis Rheum. 56, 4024-37.
1. Awad HA
2. Zhang X
3. Reynolds DG
4. Guldberg RE
5. O'Keefe RJ
6. Schwarz EM
(2007 Aug 01). Recent advances in gene delivery for structural bone allografts. Tissue Eng. 13, 1973-85.
1. DiPaola CP
2. Jacobson JA
3. Awad H
4. Conrad BP
5. Rechtine GR
(2007 Jul 01). Screw pull-out force is dependent on screw orientation in an anterior cervical plate construct. J Spinal Disord Tech. 20, 369-73.
1. Xie C
2. Reynolds D
3. Awad H
4. Rubery PT
5. Pelled G
6. Gazit D
7. Guldberg RE
8. Schwarz EM
9. O'Keefe RJ
10. Zhang X
(2007 Mar 01). Structural bone allograft combined with genetically engineered mesenchymal stem cells as a novel platform for bone tissue engineering. Tissue Eng. 13, 435-45.
1. Reynolds DG
2. Hock C
3. Shaikh S
4. Jacobson J
5. Zhang X
6. Rubery PT
7. Beck CA
8. O'keefe RJ
9. Lerner AL
10. Schwarz EM
11. Awad HA
(2007 Jan 01). Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts. J Biomech. 40, 3178-86.
1. Zhang X
2. Naik A
3. Xie C
4. Reynolds D
5. Palmer J
6. Lin A
7. Awad H
8. Guldberg R
9. Schwarz E
10. O'Keefe R
(2005 Dec 12). Periosteal stem cells are essential for bone revitalization and repair. J Musculoskelet Neuronal Interact. 5, 360-2.