IND 410 - Molecular Biology and Genetics
Spring Semester, 4 Cr.
Course Description: This course is designed primarily for graduate students. One-hour lectures cover modern topics of interest, including DNA replication; DNA repair and mutagenesis, recombination and transposable elements; regulation of gene expression on prokaryotes; and regulation of eukaryotic transcription and RNA processing. Emphasis is placed on both biochemical and genetic approaches to the study of these problems. Special additional topics include genomics as an approach to regulation and mammalian genetic techniques of analysis. In addition to the lectures, workshops are held once a week to study further examples from the literature.
BCH 515 - Critical Thinking in Research Science
Fall Semester, 1 Cr.
Course Description: Students present a history of experimental work leading to their research project. This includes a selection of published and unpublished work from their advisor's lab and other labs in the same field, providing a rationale for the project. Students conclude with a report of their published and preliminary data. Focus will be on interpreting experimental data and engaging student interactions.
- L74V increases the reverse transcriptase content of HIV-1 virions with non-nucleoside reverse transcriptase drug-resistant mutations L100I+K103N and K101E+G190S, which results in increased fitness. J Gen Virol. In press. (2013 Mar 27).
- Flap Endonuclease 1. Annu Rev Biochem. In press. (2013 Feb 28).
- Okazaki fragment metabolism. Cold Spring Harb Perspect Biol. 5, . (2013 Feb 01).