Principal Investigator
Courses
BME/CHE 432 - Controlled Release Systems
Department of Biomedical Engineering, University of Rochester
Fall Semester, 2 Cr.
Course Instructor
Course Description: This course is designed to provide students with an understanding of the principles, strategies, and materials used in controlled drug delivery systems. The course will first cover the fundamentals of drug delivery, including physiology, pharmacokinetics/pharmacodynamics, drug diffusion and permeation, and biomaterials used in drug delivery. Controlled release strategies for various administration routes will then be discussed.
BME 396 - Biomaterials
Department of Biomedical Engineering, University of Rochester
Spring Semester, 4 Cr.
Course Instructor
Course Description: This course provides a background in biomaterials: basic material properties, specifics on ceramics, polymers and metals used in the body, and special topics related to biomaterials including tissue engineering, biological responses to implanted materials, and drug delivery.
Recent Publications
- (2012 Jan 17). Pro-apoptotic gene knockdown mediated by nanocomplexed siRNA reduces radiation damage in primary salivary gland cultures. J Cell Biochem. In press.
- (2011 Jul 11). Synthesis of folate-functionalized RAFT polymers for targeted siRNA delivery. Biomacromolecules. 12, 2708-14.
- (2010 Apr 05). pH-responsive polymeric sirna carriers sensitize multidrug resistant ovarian cancer cells to doxorubicin via knockdown of polo-like kinase 1. Mol Pharm. 7, 442-55.
