Correlate Stable End Products with Their Free Radical Precursors
Project Collaborators:
- Dr. Peter Dedon Massachusetts Institute of Technology
- Dr. Steven Swarts University of Florida
- Dr. Richard Wagner Sherbrooke University
- Dr. Michael Weinfeld Cross Cancer Institute
The hypothesis that all (>99%) of the stable end products produced in DNA are derived from free radical precursors is being tested and the reaction pathways elucidated. For crystalline DNA irradiated at 4K, the prediction that the ratio of strand breaks to base damage is unusually large (about 1:1) will be tested.
Research Projects
