Honors & News
May 16, 2013
The URMC Cardiovascular Engineering Lab (CVEL) has been awarded the 2013 CTSI/UNYTE pilot Collaborative research grant. The project, entitled, Regional Ultrasound Wall Strain Measurements to Predict Risk of Abdominal Aortic Aneurysm (AAA) rupture, is led by PI's Ankur Chandra, M.D., RPVI, Karl Schwarz, M.D., Steven Day, Ph.D., and Dan Phillips, Ph.D.
UNYTE offers a pilot funding program open to investigators at research institutions across the Upstate region. The objective of the program is to catalyze the formation of multi-institutional, cross-disciplinary research teams that are focused on a critical issue in clinical or translational research. To receive funding, projects must involve collaboration from at least two UNYTE member institutions. Applicants are strongly encouraged to develop an innovative, team-based approach that reflects the research strengths of the participating institutions, as well as of the investigators themselves.
May 16, 2013
Abdominal aortic aneurysms are one of the top ten causes of death in men over the age of 55, and upstate New York has higher rates of this condition than the rest of the country. Researchers are now working on patient-specific diagnosis and treatment, as the Innovation Trail's Kate O'Connell reports.
Dr. Ankur Chandra, a lead investigator at the University of Rochester's Cardio-Vascular Engineering Lab (CVEL), says the prevalence of aortic aneurysms and ruptures in upstate New York points to a need for increased screening.
One thing about the Western New York and upstate region that's critically important is that the prevalence, meaning the number of patients in this region with aortic aneurysms is unusually high when compared with the rest of the country,Chandra says.
October 10, 2012
The University of Rochester is combining its medical, engineering, and entrepreneurial expertise to create the Center for Medical Technology Innovation (CMTI). A collaboration of the Hajim School of Engineering and Applied Sciences and the School of Medicine and Dentistry, CMTI will also make use of the University's Center for Entrepreneurship as it coordinates activities to develop technological solutions to clinical problems.
Ankur Chandra, M.D., the medical director of CMTI, said a recent development at the University of Rochester Medical Center validates the importance of the center's approach. Since multiple medical conditions such as aortic aneurysms can now be addressed by inserting devices through blood vessels - rather than by open surgery - larger catheters are needed to place through the femoral artery in the thigh, the point where the devices are inserted.
One of our students, Rachel Rakvica, noticed that the larger openings allowed for newer techniques to close the artery - a novel approach that did not require incisions,said Chandra.
We've obtained a provisional patent, with the hope of further developing the technology.
Amy Lerner, the academic director of CMTI, has had a great deal of experience guiding students in the medical device development process. An associate professor of biomedical engineering, Lerner directs the senior design course, a year-long program in which teams of students partner with clinicians, companies, and other institutions to solve real-world engineering problems.
The new center will be critical in helping take student and faculty design solutions to the next step,said Lerner.
We'll work closely with industry to address design challenges, which will also help prepare our students for careers in healthcare.
The executive director of CMTI will be Greg Gdowski, who earned a Ph.D. in biomedical engineering at Boston University and worked as a research fellow at Blue Highway, an engineering services company in Syracuse. Gdowski believes the new center will increase the national visibility and stature of the University of Rochester and its biomedical engineering program. He added,
It will also help foster growth and collaboration between faculty at the Hajim School and those at the Medical Center.
September 7, 2012
The CTSI supports medical students interested in a year-out experience of mentored clinical and translational research. Most students will enter through the Academic Research Track (ART), which is the foundation of the CTSI program. Doran Mix, a CTSI TL1 Predoctoral Program trainee, and his team completed a number of multidisciplinary projects that apply biomedical engineering concepts to solve problems in cardiovascular medicine. Mix says his experience with the CTSI has inspired him to continue to do research for the remainder of his career. To learn more about Doran Mix and his research visit his CTSI information page and the Cardiovascular Engineering Lab (CVEL).
- Ventricular assist device thrombosis following recovery of left ventricular function. ASAIO J. 60, 243-5. (2014 Feb 28).
- Predictive Multivariate Regression to Increase the Specificity of Carotid Duplex Ultrasound for High-Grade Stenosis in AsymptomaticPatients. Ann Vasc Surg. In press. (2014 Feb 12).
- CT Angiography-Derived Duplex Ultrasound Velocity Criteria in Patients with Carotid Artery Stenosis. Ann Vasc Surg. In press. (2014 Jan 20).