Principal Investigators

Charles J. Duffy, M.D., Ph.D. University of Rochester work Box 673 601 Elmwood Ave Rochester NY 14642 office: MC 6-8535 p 585-273-1696 cjd@cvs.rochester.edu

Mark Edward Mapstone, Ph.D. University of Rochester work Box 673 601 Elmwood Ave Rochester NY 14642 office: MC 6-7532 p 585-273-4859 Mark_Mapstone@urmc.rochester.edu

William K. Page, Ph.D. University of Rochester work Box 673 601 Elmwood Ave Rochester NY 14642 office: MC 6-7530 p 585-273-2418 bp@cvs.rochester.edu

Affiliations

Mechanisms of Spatial Orientation

Cognitive Neuroscience Lab, 2006

Single neuron recordings from awake monkey cerebral cortex have demonstrated the existence of neurons which are specifically activated during the viewing of optic flow fields. Our ongoing studies combine optic flow visual displays with real translational movement of the monkey using a room-sized, motorized sled. These studies are directed at characterizing the neuronal mechanisms of self-movement perception.

Our human psychophysical studies are directed at analyzing the cortical operations involved in optic flow field perception. We are focusing on studies of perceptual involvement in the syndrome of visuospatial disorientation in Alzheimer's disease and other neurodegenerative disorders.