Principal Investigator

Mark E. Dumont, Ph.D. University of Rochester work Box 712 601 Elmwood Ave Rochester NY 14642 office: MC 3-6536 p (585) 275-2466 f (585) 275-6007

Contact

Dumont Lab University of Rochester work MC 3-7518 601 Elmwood Ave Rochester NY 14642 p (585) 275-1895

Affiliations

Signal Transduction; Membrane Protein Structure, Yeast Molecular Biology

Dumont Lab, 2011

Transmembrane proteins carry out critical functions in transporting ions and metabolites in an out of cells and organelles, in transducing extracellular signals into intracellular responses, in cell-cell recognition, and in catalyzing a variety of enzymatic reactions. They also constitute 20-30% of the protein coding potential of most genomes. However, the structures and molecular mechanisms of the function of membrane proteins remain much more poorly characterized than is the case for most soluble proteins. The Dumont laboratory focuses on understanding mechanisms of membrane protein function at the molecular level.

Recent Publications