Strong mentoring is a source of pride. Lab activities include training at NMR-FAM and Reichart surface plasmon resonance facility, trips to collect synchrotron data at Cornell and Berkeley CA, remote synchrotron data collection at Stanford CA, as well as attendance at international meetings. Our weekly group meetings are augmented by monthly joint group meetings with the Wedekind laboratory to discuss methods of structural biology, and RNA Cluster meetings to learn about our colleagues’ research in structural biology.
Ph.D. graduates from the laboratory include: Dr. Karen R. Thickman, who is now assistant teaching professor at Carnegie-Mellon; Dr. Ankit Gupta, now post-doctoral fellow at University of Chicago; and Dr. Krystle McLaughlin, who is currently progressing well in the NIH-funded SPIRE post-doctoral program at UNC-Chapel Hill. The Kielkopf laboratory has been home to three minority post-doctoral fellows and a McNair minority undergraduate researcher. Among these, Dr. Kholiswa Laird currently is an NIH fellowship recipient in the laboratory, another, Dr. Shanthi Paranawithana, is an assistant professor at Hampton University, and the third, Dr. Jermaine Jenkins, is currently research assistant professor and Biophysics and Structural Biology Facility Manager at the U of R. We look forward to following the careers of lab 'alumni' in years to come.
- Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA. Proc Natl Acad Sci U S A. 111, 17420-5. (2014 Dec 09).
- U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing. Leukemia. In press. (2014 Oct 14).
- Cancer-relevant splicing factor CAPERα engages the essential splicing factor SF3b155 in a specific ternary complex. J Biol Chem. 289, 17325-37. (2014 Jun 20).