Clara L. Kielkopf, Ph.D. University of Rochester
Principal Investigatorwork Box 712 601 Elmwood Ave Rochester NY 14642 p 585-273-4799 f 585-275-6007 email@example.com Research Focus: Structural and biophysical basis of normal and disease-associated pre-mRNA recognition
Jermaine Jenkins, Ph.D. University of Rochester
Research Assistant Professorwork Box 712 601 Elmwood Ave Rochester NY 14642 office: MC 1-6818A p 585-275-5305 f 585-275-6007 firstname.lastname@example.org Research Focus: Crystallography of RNA and Protein-RNA complexes
Graduate Studentwork Rochester NY p 585-273-1266 Anant_Agrawal@urmc.rochester.edu Research Focus: Investigating the mechanism of UAP56-U2AF65 interaction at the 3’ splice site pre-mRNA
Graduate Studentwork Rochester NY Rakesh_Chatrikhi@urmc.rochester.edu Research Focus: Pre-mRNA Conformation in Complexes with the Essential Splicing Factor U2AF65
Graduate Studentwork Rochester NY email@example.com Research Focus: The Structural Basis of U2AF Homology Motif Specificity of CAPERα
- Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay. Nat Struct Mol Biol. 20, 515-24. (2013 Apr 01).
- U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res. 41, 3859-73. (2013 Apr 01).
- Structure of phosphorylated SF1 bound to U2AF⁶⁵ in an essential splicing factor complex. Structure. 21, 197-208. (2013 Feb 05).