May 6, 2015
2015 Awards Announced
The 2015 Vincent duVignaeud Award for excellence in basic research will be awarded at this year's commencement to Dr. Steven Baker who completed his Ph.D. in Luis Martinez-Sobrido's lab.
The 2015 Wallace O. Fenn Award for excellence in basic research will be awarded at this year's commencement to Dr. Julie Sahler who completed her Ph.D. in Richard Phipps' lab.
Award Recipients for the Melville A. Hare Award for Excellence in Research have been awarded to Dr. Denise Skrombolas who completed her Ph.D. in the lab of John Frelinger and Dr. Benson Cheng who completed his Ph.D. in Luis Martinez-Sobrido's lab.
The Melville A. Hare Award for Excellence in Teaching has been awarded to Jennifer Colquhoun. Jennifer is in Paul Dunman's laboratory.
A Departmental Peer Mentoring Award was established this year. The recipient of the 2015 award is Lisbeth Boule. Lisbeth is in Paige Lawrence's laboratory.
October 23, 2013
Bethany Winans Receives Young Investigator Award
September 30, 2013
Paige Lawrence Receives New R01 Grant from NIEHS
Dr. Paige Lawrence, professor in the departments of Environmental Medicine and Microbiology & Immunology has received a new R01 grant from the National Institutes for Environmental Health Sciences (NIEHS), entitled Transgenerational exposures as modifiers of host defense against infection.
Along with UR Collaborators Steve Gill, Ph.D. and Sally Thurston, Ph.D., this project will explore exposure to pollutants can cause transgenerational changes in biological processes and contribute to disease. Since very little of this research has focused on transgenerational epigenetic inheritance of changes in immune function, the proposed research will direct address this deficit, and will study how a family of common pollutants perturbs the development and function of the immune system across generations.
The objective of this project is to define key parameters involved in transgenerational inheritance of alterations in the function of the mammalian immune system that occur as a result of environmental exposure. The immune system is fundamentally important to public and individual health, and even slight modifications in its function can have a profoundly negative impact on health and disease. For instance, influenza virus infections pose significant global health threats, infecting over 1 billion people annually. Evidence points to prenatal and early life exposure to pollutants as overlooked contributors to poorer clinical outcomes following influenza and other respiratory infections.
August 3, 2011
How exposure to chemicals and other environmental factors from the earliest months of life – even before we are born – affect our long-term health is the subject of a new five-year study by a scientist at the University of Rochester Medical Center.
B. Paige Lawrence, Ph.D., associate professor of Environmental Medicine and of Microbiology and Immunology, has been awarded $1.75 million by the National Institutes of Health to study how early exposure to factors in the environment affect our immune system.
- Developmental activation of the AHR increases effector CD4+ T cells and exacerbates symptoms in autoimmune disease-prone Gnaq+/- mice.Toxicol Sci. (2015 Sep 11).
- Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection.Am J Physiol Lung Cell Mol Physiol. 309, L305-13. (2015 Aug 01).
- Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.J Immunol. 194, 4446-57. (2015 May 01).