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Principal Investigator

Benjamin L. Miller, Ph.D. University of Rochester work Box 697 601 Elmwood Ave Rochester NY 14642 office: MC 6-6820 p 585-275-9805 benjamin_miller@urmc.rochester.edu

Recent Publications

The following list was auto-generated 1 week ago.

• 1. Pal S
  2. Yadav AR
  3. Lifson MA
  4. Baker JE
  5. Fauchet PM
  6. Miller BL
  (2013 Jun 15). Selective virus detection in complex sample matrices with photonic crystal optical cavities. Biosens Bioelectron. 44, 229-34.
• 1. Possin KL
  2. Feigenbaum D
  3. Rankin KP
  4. Smith GE
  5. Boxer AL
  6. Wood K
  7. Hanna SM
  8. Miller BL
  9. Kramer JH
  (2013 May 08). Dissociable executive functions in behavioral variant frontotemporal and Alzheimer dementias. Neurology. In press.
• 1. Lee SE
  2. Tartaglia MC
  3. Yener G
  4. Genç S
  5. Seeley WW
  6. Sanchez-Juan P
  7. Moreno F
  8. Mendez MF
  9. Klein E
  10. Rademakers R
  11. Munain AL
  12. Combarros O
  13. Kramer JH
  14. Kenet RO
  15. Boxer AL
  16. Geschwind MD
  17. Gorno-Tempini ML
  18. Karydas AM
  19. Rabinovici GD
  20. Coppola G
  21. Geschwind DH
  22. Miller BL
  (2013 Mar 25). Neurodegenerative Disease Phenotypes in Carriers of MAPT p.A152T, A Risk Factor for Frontotemporal Dementia Spectrum Disorders and Alzheimer Disease. Alzheimer Dis Assoc Disord. In press.
• 1. Pal S
  2. Fauchet PM
  3. Miller BL
  (2012 Nov 06). 1-D and 2-D photonic crystals as optical methods for amplifying biomolecular recognition. Anal Chem. 84, 8900-8.
• 1. Ofori LO
  2. Hoskins J
  3. Nakamori M
  4. Thornton CA
  5. Miller BL
  (2012 Jul 01). From dynamic combinatorial 'hit' to lead: in vitro and in vivo activity of compounds targeting the pathogenic RNAs that cause myotonic dystrophy. Nucleic Acids Res. 40, 6380-90.
• 1. Deane R
  2. Singh I
  3. Sagare AP
  4. Bell RD
  5. Ross NT
  6. LaRue B
  7. Love R
  8. Perry S
  9. Paquette N
  10. Deane RJ
  11. Thiyagarajan M
  12. Zarcone T
  13. Fritz G
  14. Friedman AE
  15. Miller BL
  16. Zlokovic BV
  (2012 Apr 02). A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease. J Clin Invest. 122, 1377-92.
• 1. Peng HI
  2. Strohsahl CM
  3. Miller BL
  (2012 Mar 21). Microfluidic nanoplasmonic-enabled device for multiplex DNA detection. Lab Chip. 12, 1089-93.
• 1. Gromova AV
  2. Ciszewski JM
  3. Miller BL
  (2012 Feb 18). Ternary resin-bound Dynamic Combinatorial Chemistry. Chem Commun (Camb). 48, 2131-3.
• 1. Miller BL
  (2012 Jan 01). DCC in the development of nucleic acid targeted and nucleic acid inspired structures. Top Curr Chem. 322, 107-37.
• 1. Pal S
  2. Guillermain E
  3. Sriram R
  4. Miller BL
  5. Fauchet PM
  (2011 Jun 15). Silicon photonic crystal nanocavity-coupled waveguides for error-corrected optical biosensing. Biosens Bioelectron. 26, 4024-31.
• 1. Sriram R
  2. Yadav AR
  3. Mace CR
  4. Miller BL
  (2011 May 15). Validation of arrayed imaging reflectometry biosensor response for protein-antibody interactions: cross-correlation of theory, experiment, and complementary techniques. Anal Chem. 83, 3750-7.
• 1. Peng HI
  2. Miller BL
  (2011 Feb 07). Recent advancements in optical DNA biosensors: exploiting the plasmonic effects of metal nanoparticles. Analyst. 136, 436-47.
• 1. Mace CR
  2. Topham DJ
  3. Mosmann TR
  4. Quataert SA
  5. Treanor JJ
  6. Miller BL
  (2011 Jan 15). Label-free, arrayed sensing of immune response to influenza antigens. Talanta. 83, 1000-5.
• 1. Peng HI
  2. Krauss TD
  3. Miller BL
  (2010 Oct 15). Aging induced Ag nanoparticle rearrangement under ambient atmosphere and consequences for nanoparticle-enhanced DNA biosensing. Anal Chem. 82, 8664-70.
• 1. Palde PB
  2. Ofori LO
  3. Gareiss PC
  4. Lerea J
  5. Miller BL
  (2010 Aug 26). Strategies for recognition of stem-loop RNA structures by synthetic ligands: application to the HIV-1 frameshift stimulatory sequence. J Med Chem. 53, 6018-27.
• 1. Miller BL
  (2010 Jun 01). Dynamic covalent chemistry: Catalysing dynamic libraries. Nat Chem. 2, 433-4.
• 1. McNaughton BR
  2. Gareiss PC
  3. Jacobs SE
  4. Fricke AF
  5. Scott GA
  6. Miller BL
  (2009 Oct 01). A potent activator of melanogenesis identified from small-molecule screening. ChemMedChem. 4, 1583-9.
• 1. Peng HI
  2. Strohsahl CM
  3. Leach KE
  4. Krauss TD
  5. Miller BL
  (2009 Aug 25). Label-free DNA detection on nanostructured Ag surfaces. ACS Nano. 3, 2265-73.
• 1. Wender PA
  2. Miller BL
  (2009 Jul 09). Synthesis at the molecular frontier. Nature. 460, 197-201.
• 1. Strohsahl CM
  2. Krauss TD
  3. Miller BL
  (2009 Feb 24). Detection of methicillin-resistant Staphylococcus aureus (MRSA) using the NanoLantern Biosensor. Proc. SPIE. 7167, 71670S.
• 1. Peng H-I
  2. Nuffer ZM
  3. Miller BL
  (2009 Feb 18). The role of alkanethiol spacers in a metal surface-based label-free DNA detection system. Proc. SPIE. 7167, 71670H.
• 1. Striemer CC
  2. Mace CR
  3. Carter JA
  4. Mehta SD
  5. Miller BL
  (2009 Feb 18). Arrayed imaging reflectometry for inexpensive and label-free protein arrays. Proc. SPIE. 7167, 71670G.
• 1. Mace CR
  2. Rose RC
  3. Miller BL
  (2009 Feb 18). Tracking serum antibody response to viral antigens with arrayed imaging reflectometry. Proc. SPIE. 7167, 71670H.
• 1. Gareiss PC
  2. Miller BL
  (2009 Feb 01). Ribosomal frameshifting: an emerging drug target for HIV. Curr Opin Investig Drugs. 10, 121-8.
• 1. Miller BL
  (2009 Jan 01). Diagnostics for a personalized medical future: extending our senses to the molecular scale. Stud Health Technol Inform. 149, 297-310.
• 1. Gareiss PC
  2. Sobczak K
  3. McNaughton BR
  4. Palde PB
  5. Thornton CA
  6. Miller BL
  (2008 Dec 03). Dynamic combinatorial selection of molecules capable of inhibiting the (CUG) repeat RNA-MBNL1 interaction in vitro: discovery of lead compounds targeting myotonic dystrophy (DM1). J Am Chem Soc. 130, 16254-61.
• 1. Mace CR
  2. Yadav AR
  3. Miller BL
  (2008 Nov 18). Investigation of non-nucleophilic additives for the reduction of morphological anomalies in protein arrays. Langmuir. 24, 12754-7.
• 1. Mace CR
  2. Striemer CC
  3. Miller BL
  (2008 Oct 15). Detection of human proteins using arrayed imaging reflectometry. Biosens Bioelectron. 24, 334-7.
• 1. Palde PB
  2. Gareiss PC
  3. Miller BL
  (2008 Jul 23). Selective recognition of alkyl pyranosides in protic and aprotic solvents. J Am Chem Soc. 130, 9566-73.
• 1. Ross NT
  2. Miller BL
  (2007 Dec 01). Characterization of the binding surface of the translocated intimin receptor, an essential protein for EPEC and EHEC cell adhesion. Protein Sci. 16, 2677-83.
• 1. Ross NT
  2. Mace CR
  3. Miller BL
  (2007 Nov 03). Biophysical analysis of the EPEC translocated intimin receptor-binding domain. Biochem Biophys Res Commun. 362, 1073-8.
• 1. Strohsahl CM
  2. Krauss TD
  3. Miller BL
  (2007 Sep 30). Identification of high-stringency DNA hairpin probes by partial gene folding. Biosens Bioelectron. 23, 233-40.
• 1. McNaughton BR
  2. Gareiss PC
  3. Miller BL
  (2007 Sep 19). Identification of a selective small-molecule ligand for HIV-1 frameshift-inducing stem-loop RNA from an 11,325 member resin bound dynamic combinatorial library. J Am Chem Soc. 129, 11306-7.
• 1. Striemer CC
  2. Mace CR
  3. Miller BL
  (2007 May 01). Rapid Label-free Protein Detection Arrays on Coated Silicon Wafers. Mat. Res. Soc. Symp. Proc.. 951E, 0951-E09-07.
• 1. Palde PB
  2. McNaughton BR
  3. Ross NT
  4. Gareiss PC
  5. Mace CR
  6. Spitale RC
  7. Miller BL
  (2007 Mar 08). Single-Step Synthesis of Functional Organic Receptors via a Tridirectional Minisci Reaction. Synthesis. 15, 2287.
• 1. Ouyang H
  2. Delouise LA
  3. Miller BL
  4. Fauchet PM
  (2007 Feb 15). Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensors. Anal Chem. 79, 1502-6.
• 1. Strohsahl CM
  2. Miller BL
  3. Krauss TD
  (2007 Jan 01). Preparation and use of metal surface-immobilized DNA hairpins for the detection of oligonucleotides. Nat Protoc. 2, 2105-10.
• 1. Gareiss PC
  2. Palde PB
  3. Hubbard RD
  4. Miller BL
  (2007 Jan 01). Conformational and Structural Analysis of a ter-Cyclopentane Scaffold for Molecular Recognition. Eur. J. Org. Chem. 2007, 53.
• 1. Bucholtz KM
  2. Gareiss PC
  3. Tajc SG
  4. Miller BL
  (2006 Nov 07). Synthesis and evaluation of the first cis-cyclobutane-containing receptor for lipid A. Org Biomol Chem. 4, 3973-9.
• 1. Mace CR
  2. Striemer CC
  3. Miller BL
  (2006 Aug 01). Theoretical and experimental analysis of arrayed imaging reflectometry as a sensitive proteomics technique. Anal Chem. 78, 5578-83.
• 1. McNaughton BR
  2. Miller BL
  (2006 Apr 27). Resin-bound dynamic combinatorial chemistry. Org Lett. 8, 1803-6.
• 1. Tajc SG
  2. Miller BL
  (2006 Mar 01). A designed receptor for pH-switchable ion binding in water. J Am Chem Soc. 128, 2532-3.
• 1. Horner SR
  2. Mace CR
  3. Rothberg LJ
  4. Miller BL
  (2006 Feb 15). A proteomic biosensor for enteropathogenic E. coli. Biosens Bioelectron. 21, 1659-63.
• 1. Tolbert BS
  2. Tajc SG
  3. Webb H
  4. Snyder J
  5. Nielsen JE
  6. Miller BL
  7. Basavappa R
  (2005 Dec 20). The active site cysteine of ubiquitin-conjugating enzymes has a significantly elevated pKa: functional implications. Biochemistry. 44, 16385-91.
• 1. Ouyang H
  2. Christophersen M
  3. Viard R
  4. Miller BL
  5. Fauchet PM
  (2005 Sep 22). Macroporous Silicon Microcavities for Macromolecule Detection. Advanced Functional Materials. 15, 1851.
• 1. Strohsahl CM
  2. Du H
  3. Miller BL
  4. Krauss TD
  (2005 Sep 15). Towards single-spot multianalyte molecular beacon biosensors. Talanta. 67, 479-85.
• 1. Ouyang H
  2. Lee M
  3. Miller BL
  4. Fauchet PM
  (2005 Sep 12). Silicon Photonic Bandgap Biosensors. Proc. SPIE. 2018, 93.
• 1. DeLouise LA
  2. Fauchet PM
  3. Miller BL
  4. Pentland AA
  (2005 Aug 08). Hydrogel-Supported Optical Microcavity Sensors. Advanced Materials. 17, 2199.
• 1. Du H
  2. Strohsahl CM
  3. Camera J
  4. Miller BL
  5. Krauss TD
  (2005 Jun 01). Sensitivity and specificity of metal surface-immobilized "molecular beacon" biosensors. J Am Chem Soc. 127, 7932-40.
• 1. DeLouise LA
  2. Kou PM
  3. Miller BL
  (2005 May 15). Cross-correlation of optical microcavity biosensor response with immobilized enzyme activity. Insights into biosensor sensitivity. Anal Chem. 77, 3222-30.