Principal Investigator

Joshua C. Munger, Ph.D. University of Rochester work Box 712 Rochester NY p 585-273-4800 f 585-275-6007 Joshua_Munger@urmc.rochester.edu

Recent Publications

The following list was auto-generated 11 hours ago.

1. Sasaki M
2. Knobbe CB
3. Munger JC
4. Lind EF
5. Brenner D
6. Brüstle A
7. Harris IS
8. Holmes R
9. Wakeham A
10. Haight J
11. You-Ten A
12. Li WY
13. Schalm S
14. Su SM
15. Virtanen C
16. Reifenberger G
17. Ohashi PS
18. Barber DL
19. Figueroa ME
20. Melnick A
21. Zúñiga-Pflücker JC
22. Mak TW
(2012 Aug 30). IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics. Nature. 488, 656-9.
1. McArdle J
2. Moorman NJ
3. Munger J
(2012 Jan 01). HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication. PLoS Pathog. 8, e1002502.
1. Wang R
2. Dillon CP
3. Shi LZ
4. Milasta S
5. Carter R
6. Finkelstein D
7. McCormick LL
8. Fitzgerald P
9. Chi H
10. Munger J
11. Green DR
(2011 Dec 23). The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity. 35, 871-82.
1. Hollenbaugh JA
2. Munger J
3. Kim B
(2011 Jul 05). Metabolite profiles of human immunodeficiency virus infected CD4+ T cells and macrophages using LC-MS/MS analysis. Virology. 415, 153-9.
1. Spencer CM
2. Schafer XL
3. Moorman NJ
4. Munger J
(2011 Jun 01). Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication. J Virol. 85, 5814-24.
1. McArdle J
2. Schafer XL
3. Munger J
(2011 Jan 01). Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny. J Virol. 85, 705-14.
1. Munger J
2. Bennett BD
3. Parikh A
4. Feng XJ
5. McArdle J
6. Rabitz HA
7. Shenk T
8. Rabinowitz JD
(2008 Oct 01). Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy. Nat Biotechnol. 26, 1179-86.
1. Munger J
2. Bajad SU
3. Coller HA
4. Shenk T
5. Rabinowitz JD
(2006 Dec 01). Dynamics of the cellular metabolome during human cytomegalovirus infection. PLoS Pathog. 2, e132.
1. Munger J
2. Yu D
3. Shenk T
(2006 Apr 01). UL26-deficient human cytomegalovirus produces virions with hypophosphorylated pp28 tegument protein that is unstable within newly infected cells. J Virol. 80, 3541-8.
1. Benetti L
2. Munger J
3. Roizman B
(2003 Jun 01). The herpes simplex virus 1 US3 protein kinase blocks caspase-dependent double cleavage and activation of the proapoptotic protein BAD. J Virol. 77, 6567-73.
1. Munger J
2. Hagglund R
3. Roizman B
(2003 Jan 20). Infected cell protein No. 22 is subject to proteolytic cleavage by caspases activated by a mutant that induces apoptosis. Virology. 305, 364-70.
1. Hagglund R
2. Munger J
3. Poon AP
4. Roizman B
(2002 Jan 01). U(S)3 protein kinase of herpes simplex virus 1 blocks caspase 3 activation induced by the products of U(S)1.5 and U(L)13 genes and modulates expression of transduced U(S)1.5 open reading frame in a cell type-specific manner. J Virol. 76, 743-54.
1. Munger J
2. Roizman B
(2001 Aug 28). The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins. Proc Natl Acad Sci U S A. 98, 10410-5.
1. Munger J
2. Chee AV
3. Roizman B
(2001 Jun 01). The U(S)3 protein kinase blocks apoptosis induced by the d120 mutant of herpes simplex virus 1 at a premitochondrial stage. J Virol. 75, 5491-7.
1. Galvan V
2. Brandimarti R
3. Munger J
4. Roizman B
(2000 Feb 01). Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells. J Virol. 74, 1931-8.