Principal Investigators

M. Kerry O'Banion, M.D., Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 5-8527A p 585-275-5185 Kerry_obanion@urmc.rochester.edu

John A. Olschowka, Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 5-6312 p 585-275-8238 john_olschowka@urmc.rochester.edu

Recent Presentations

Wu M., Olschowka J. & O'Banion M.K. 2009. Overexpression of hippocampal interleukin-1β does not exacerbate experimental autoimmune encephalomyelitis. Poster session presented at the 39^th Annual Meeting of the Society for Neuroscience, Chicago, IL.
Ghosh S., Wu, M.D., Trojanczyk L.A., Johnson R.E., Olschowka J.A. & O'Banion M.K. 2009. Sustained overexpression of interleukin-1β ameliorates amyloid pathology in the triple transgenic mouse model of AD. Poster session presented at the 39^th Annual Meeting of the Society for Neuroscience, Chicago, IL.
O'Banion M.K., Matousek S.B., Shaftel S.S., Kyrkanides S. & Olschowka J.A. 2009. Sustained interleukin-1 expression drives plaque clearance in a mouse model of Alzheimer's disease. Poster session presented at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD), Vienna, Austria.
Hurley S.D., Moravan M.J., Trojanczyk L.A., Olschowka J.A., Williams J.P. & O'Banion M.K. 2009. Acute neuroinflammation following gamma or HZE particle irradiation. Poster session presented at the 20^th Annual NASA Space Radiation Investigator's Meeting, Köln, Germany.
O'Banion M.K., Hurley S.D., Olschowka J.A. & Williams J. 2009. Low dose ionizing radiation and HZE particle effects on adult hippocampal neurogenesis. Poster session presented at the Low Dose Radiation Research Investigators Workshop VIII, Bethesda, MD.
Matousek S.B., Shaftel S.S., Olschowka J.A., & O'Banion M.K. 2009. Interleukin-1 mediated activation of innate immunity underlies plaque clearance in Alzheimer's disease. Poster session presented at the American Society for Neurochemistry 40^th Annual Meeting, Charleston, SC.

Recent Publications

1. Wu MD
2. Hein AM
3. Moravan MJ
4. Shaftel SS
5. Olschowka JA
6. O'Banion MK
(2012 Feb 01). Adult murine hippocampal neurogenesis is inhibited by sustained IL-1β and not rescued by voluntary running. Brain Behav Immun. 26, 292-300.
1. Hein AM
2. O'Banion MK
(2012 Jan 18). Neuroinflammation and Cognitive Dysfunction in Chronic Disease and Aging. J Neuroimmune Pharmacol. In press.
1. Matousek SB
2. Ghosh S
3. Shaftel SS
4. Kyrkanides S
5. Olschowka JA
6. O'Banion MK
(2011 Dec 16). Chronic IL-1β-Mediated Neuroinflammation Mitigates Amyloid Pathology in a Mouse Model of Alzheimer's Disease without Inducing Overt Neurodegeneration. J Neuroimmune Pharmacol. In press.

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