Principal Investigators

M. Kerry O'Banion, M.D., Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 5-8527A p 585-275-5185 Kerry_obanion@urmc.rochester.edu

John A. Olschowka, Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 5-6312 p 585-275-8238 john_olschowka@urmc.rochester.edu

Recent Presentations

Wu M., Olschowka J. & O'Banion M.K. 2009. Overexpression of hippocampal interleukin-1β does not exacerbate experimental autoimmune encephalomyelitis. Presented at the 39^th Annual Meeting of the Society for Neuroscience, Chicago, IL.
Ghosh S., Wu, M.D., Trojanczyk L.A., Johnson R.E., Olschowka J.A. & O'Banion M.K. 2009. Sustained overexpression of interleukin-1β ameliorates amyloid pathology in the triple transgenic mouse model of AD. Presented at the 39^th Annual Meeting of the Society for Neuroscience, Chicago, IL.
O'Banion M.K., Matousek S.B., Shaftel S.S., Kyrkanides S. & Olschowka J.A. 2009. Sustained interleukin-1 expression drives plaque clearance in a mouse model of Alzheimer's disease. Presented at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD), Vienna, Austria.
Hurley S.D., Moravan M.J., Trojanczyk L.A., Olschowka J.A., Williams J.P. & O'Banion M.K. 2009. Acute neuroinflammation following gamma or HZE particle irradiation. Presented at the 20^th Annual NASA Space Radiation Investigator's Meeting, Köln, Germany.
O'Banion M.K., Hurley S.D., Olschowka J.A. & Williams J. 2009. Low dose ionizing radiation and HZE particle effects on adult hippocampal neurogenesis. Presented at the Low Dose Radiation Research Investigators Workshop VIII, Bethesda, MD.
Matousek S.B., Shaftel S.S., Olschowka J.A., & O'Banion M.K. 2009. Interleukin-1 mediated activation of innate immunity underlies plaque clearance in Alzheimer's disease. Presented at the American Society for Neurochemistry 40^th Annual Meeting, Charleston, SC.

Recent Publications

1. Latchney SE
2. Hein AM
3. O'Banion MK
4. Dicicco-Bloom E
5. Opanashuk LA
(2013 May 01). Deletion or activation of the aryl hydrocarbon receptor alters adult hippocampal neurogenesis and contextual fear memory. J Neurochem. 125, 430-45.
1. Brouxhon SM
2. Kyrkanides S
3. Teng X
4. Raja V
5. O'Banion MK
6. Clark R
7. Byers SW
8. Silberfeld A
9. Tornos C
10. Ma L
(2013 Apr 25). Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: Involvement of the HER/PI3K/Akt/mTOR and IAP pathways. Clin Cancer Res. In press.
1. Montgomery SL
2. Narrow WC
3. Mastrangelo MA
4. Olschowka JA
5. O'Banion MK
6. Bowers WJ
(2013 Apr 05). Chronic Neuron- and Age-Selective Down-Regulation of TNF Receptor Expression in Triple-Transgenic Alzheimer's Disease Mice Leads to Significant Modulation of Amyloid- and Tau-Related Pathologies. Am J Pathol. In press.

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