Principal Investigators

Gary D. Paige, M.D., Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 5-7425A p 585-275-6395 f 585-442-9480
William E. O'Neill, Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 6-8531 p 585-275-4023
Scott H. Seidman, Ph.D. University of Rochester work Box 603 601 Elmwood Ave Rochester NY 14642 office: MC 6-8543 p 585-273-2122 f 585-756-5334

Available Rotations

Multisensory Interaction and Adaptive Plasticity in Spatial Localization and Orientation

The sensori-neural processes underlying our abilities to localize, track, and interact with a cluttered environment are crucial attributes of daily life, and are among the most fundamental tasks of the nervous system. The integration of multiple sensory inputs are required to guide spatial behaviors, ranging from mundane tasks such as reaching for objects, and complex ones such as navigating to and from the cafeteria for lunch. The goal of our research is to understand how the brain integrates sensory inputs from the outside world (location and motion of visual and auditory targets) with those of the internal senses (vestibular and somatosensory depictions of orientation and motion of the body and its parts,) to achieve meaningful spatial perceptions and behaviors (eye, head and postural movement).

An equally important interest is how plastic neural mechanisms register errors and adaptively adjust performance in order to maintain proper spatial calibration across sensory modalities. Finally, an important translational concern is how the neural degeneration of natural aging affects spatial behavior and plasticity. Our research environment is unique in structure and instrumentation, as well as broad and translational in character. We benefit from a collegiate and multi-disciplinary group of faculty working on problems of common interest.

For specific questions, please contact Prof. Paige.