Welcome to the Jumping Frog Lab
The overall goal of our research is to understand the co-evolutionary relationships between the structure of selected molecules (e.g., non-classical MHC class Ib molecules) and their functions in innate and adaptive immunity against tumors and viruses using the frog Xenopus as animal model.
Current Research Projects
- Nonclassical MHC-Restricted Invariant Vα6 T Cells Are Critical for Efficient Early Innate Antiviral Immunity in the Amphibian Xenopus laevis.J Immunol. (2015 Jun 10).
- Prominent amphibian (Xenopus laevis) tadpole type III interferon response to the frog virus 3 ranavirus.J Virol. 89, 5072-82. (2015 May 01).
- Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration.Dev Biol. (2015 Jan 17).