Welcome to the Jumping Frog Lab
The overall goal of our research is to understand the co-evolutionary relationships between the structure of selected molecules (e.g., non-classical MHC class Ib molecules) and their functions in innate and adaptive immunity against tumors and viruses using the frog Xenopus as animal model.
Current Research Projects
- Characterization of Frog Virus 3 knockout mutants lacking putative virulence genes.Virology. 485, 162-70. (2015 Nov 01).
- Retention of duplicated ITAM-containing transmembrane signaling subunits in the tetraploid amphibian species Xenopus laevis.Dev Comp Immunol. 53, 158-68. (2015 Nov 01).
- Distinct functional roles of amphibian (Xenopus laevis) colony-stimulating factor-1- and interleukin-34-derived macrophages.J Leukoc Biol. 98, 641-9. (2015 Oct 01).