Principal Investigator

Toru Takimoto, D.V.M., Ph.D. University of Rochester work Box 672 601 Elmwood Ave Rochester NY 14642 p (585) 273-2856 f (585) 273-9573

Research Projects

  • Molecular Mechanism of Paramyxovirus Assembly

    Molecular Mechanism of Paramyxovirus Assembly

    Sendai virus (SeV) is a pneumotropic murine pathogen in the Paramyxoviridae family, which includes many clinically important human pathogens. It is an enveloped negative-strand RNA virus and encodes 6 major structural proteins: two glycoproteins (HN and F), the matrix (M) protein, the nucleoprotein (NP), and the phosphoprotein (P) and large (L) proteins, which make up the polymerase complex. More info...

  • Role of Influenza Polymerase in Host Adaptation

    Role of Influenza Polymerase in Host Adaptation

    Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses that infect a wide range of hosts, including humans and many avian species. One mechanism for the instigation of a pandemic is direct infection of humans with an avian virus that contains mutations allowing it to easily infect and spread among humans. More info...