Anatomy and Neurochemistry of Major Psychiatric Illnesses
The Fudge Lab studies the Anatomy and neurochemistry of brain regions associated with symptoms in major psychiatric illnesses such as schizophrenia and mood disorders. Studies include the role of the amygdala in aberrant emotional processing which plays a key role in symptoms such as psychosis, and the severe mood and anxiety disorders. Areas of interest include the afferent influence of the amygdala and related limbic structures on the dopamine system, and defining new limbic regions of the striatum based on amygdaloid inputs. Ongoing studies also include identifying amygdaloid subregions whose molecular and connectional features place them in a vulnerable position for aberrant plastic changes after exposure to chronic stress.
- Differences in amygdala cell proliferation between adolescent and young adult rats. Dev Psychobiol. 56, 517-28. (2014 Apr 01).
- Altered brain response to reward and punishment in adolescents with Anorexia nervosa. Psychiatry Res. 214, 331-40. (2013 Dec 30).
- Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am J Psychiatry. 170, 1143-51. (2013 Oct 01).