Welcome to the Jumping Frog Lab
The overall goal of our research is to understand the co-evolutionary relationships between the structure of selected molecules (e.g., non-classical MHC class Ib molecules) and their functions in innate and adaptive immunity against tumors and viruses using the frog Xenopus as animal model.
Current Research Projects
- Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration. Dev Biol. In press. (2015 Jan 17).
- Divergent antiviral roles of amphibian (Xenopus laevis) macrophages elicited by colony-stimulating factor-1 and interleukin-34. J Leukoc Biol. 96, 1143-53. (2014 Dec 01).
- Evolution of nonclassical MHC-dependent invariant T cells. Cell Mol Life Sci. 71, 4763-80. (2014 Dec 01).