Maggirwar Lab
Research Focus -
Platelets, HIV and Inflammation:
A HANDful of projects in the Maggirwar Lab
This is us
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 Donna Davidson Grad Student CD40L induced changes in BBB permeability |
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 Michelle Kiebala Research Assistant Professor NF-kappaB signaling in platelets during HIV infection |
This is what we do
Despite the use of antiretroviral therapies, a majority of HIV infected individuals still develop HIV-associated neurocognitive disorders (HAND), indicating that host inflammatory mediators, in addition to viral proteins, may be contributing to these disorders. Our lab is interested in determining the mechanisms by which host factors are contributing to these disorders, with a large focus on alterations to the blood brain barrier (BBB) during infection that allow infiltration of the CNS by activated leukocytes. Specifically, we are focusing on the dysregulation of signaling events within platelets, leading to pro-inflammatory complications, as well as other cell types that are involved in regulation of the BBB such as pericytes, astrocytes, and endothelial cells that make up the neurovascular unit.
Former Members of the Lab
Ph.D. Students:
2002-2006 Ziye Sui, Neuroscience (Current position: Private Sector, China)
2003-2008 Lynn Sniderhan Gottfried, IMV (Current position: Technical Specialist, LeClair Ryan
Law Firm, Rochester, NY)
2006-2010 Michelle M. Kiebala, IMV (Current position: Research Assistant Professor,
Microbiology & Immunology, University of Rochester Medical Center, Rochester, NY)
2007-2009 Emily Desmet, IMV (Current position: Postdoc, Cornell University, Ithaca, NY)
Postdocs:
2001-2001 Suresh Joshi (Current position: Director, Surgical & Nosocomial Infections
Pathogenesis Program, Drexel University).
2002-2004 Attila Kovacs (Current position: Assistant Scientist, Sanford Health, University of
South Dakota).
2008-2009 Lynn Sniderhan Gottfried (Current position: Technical Specialist, LeClair Ryan Law
Firm, Rochester, NY)
2010-2012: Michelle Kiebala, (Current position: Research Assistant Professor,
Microbiology & Immunology, University of Rochester Medical Center, Rochester, NY)
Undergraduates Students:
2001 James Bradley, SURF Participant
2002 James Bradley, Undergraduate Independent Research (MBI 395)
2002 Stephen Bowen, SURF Participant
2003 Mahmoud El Yassir, SURF Participant
2003 Ning Jin, GEBS Summer Scholar Program Participant
2004 Ning Jin, Master's Course by Research (RIT)
2004 Yara Z. Feliciano, SURF Participant
2005 Dan Marker, GEBS Participant
2006 Donna Davidson, GEBS Participant
2009 Owen Deland, Undergraduate Independent Research (MBI 395)
2010-11 Julianna Dainotto, Undergraduate Independent Research (MBI 395)
2011-12 Dorota Stobierska, Undergraduate Independent Research (MBI 395)
Laboratory Technicians:
1998-00 Servio Ramirez
1999-00 Christopher Dimitri
2000-02 Lynn Sniderhan Gottfried
2000-03 Andrea Williamson
2002-04 Shikha Chakraborty-Sett
2005-06 Yara Z. Feliciano (PREP Trainee)
2006-07 Julyann Perez-Mayoral (PREP Trainee)
2006 Michael Burgart
2007-07 Jenny Min
2007-09 Malik Kabir
2009 Christopher Burgart
2009-2010 Joseph Jackson (PREP Trainee)
2009-2011 Michael Hirschman
20092011 Cherissre Tyrell-Boateng (PREP trainee)
Sanjay Maggirwar
Associate Professor of
Microbiology & Immunology
Contact Information:
University of Rochester
School of Medicine
and Dentistry
601 Elmwood Ave, Box 672
Rochester, New York 14642
Phone: (585) 273-2276
Fax: (585) 473-9573
