Chen Lab

Luojing Chen, Ph.D.

Ph.D. 1992
Iowa State University


Research Assistant Professor
Division of Allergy/Immunology and Rheumatology

Research Overview

Dr. Chen's research interests involve B cell signaling pathways. Dr. Chen’s laboratory is currently focusing on the role of PKK (a protein kinase) in lymphoma and lupus diseases.

Recent Publications

   Moran, S.T., Haider, J., Ow, Y., Milton, P., Chen, L., Pillai, S. "Proten kinase C-associated kinase can activate NFkappa B in both a kinase-dependent and a kinase-idependent manner." J Bil Chem. 2003 Jun 13;278(24):21526-23. View article in PubMed.

   Cariappa, A., Chen, L., Haider, K. Tang, M. , Nebelitshiy, E., Moran, S.T., Pillai, S. "A catalytically inactive form of protein kinase C-associated kinase/receptor interacting protein 4, a protein kinase C beta-associated kinase that mediates NF-Kappa B activation, interferes with early B cell development." J Immunol. 2003 Aug 15;171(4):1875-80. View article in PubMed.

   Lee, S.C., Bottaro, A., chen, L., Insel, R. "Mad 1 is a transcriptional repressor of Bcl-6." Mol Immunol. 2006 May; 43(12):1965-71. View article in PubMed .


   Chen, L., Kim, T.J., Pillai, S. "Inhibition of caspase activity prevents anti-IgM induced apoptosis but not ceramide generation in WEHI 231 B cells." Mol Immunol. 1998 Mar;35(4);195-205. View article in PubMed.

   Chen, L., Ford, C., Nikolov, Z. "Adsorption to starch of a beta-galactosidase fusion protein containing the starch-binding region of Aspergillus glucoamylase." Gene. 1991 Mar 1;99(1):121-6. View article in PubMed.

 

Contact

Luojing Chen, Ph.D.
University of Rochester
601 Elmwood Ave., Box 695
Rochester, NY 14642
Office: 585-275-0520
Luojing_Chen@urmc.
rochester.edu

Lab Members


Technicians: David Oleksyn