Email this pageRandall Lab
The Team
Troy Randall, Ph.D.
Andre Ballesteros-Tato, Ph.D. Postdoctoral fellow
Luz Garcia-Hernandez, Ph.D. Postdoctoral fellow
Louise Hartson, B.A. Senior Technical Associate
Jessica Hoffman, B.S. Senior Technical Associate (Lab manager)
Denise Kaminski, Ph.D. Instructor
Kim Kusser, B.S. Senior Technical Associate
Mark Lamere, B.A. Technical Associate
Javier Rangel-Moreno, Ph.D. Postdoctoral fellow
Dr. Randall's Research Interests
The Randall Lab is studying the development of local lymphoid tissues in the respiratory tract and determining how these tissues function to regulate respiratory immune responses. These tissues include the Bronchus Associated Lymphoid Tissue (BALT) and the Nasal Associated Lymphoid Tissue (NALT), which are found in the lungs and nasal passages respectively. Importantly, both BALT and NALT regulate different aspects of respiratory immunity in the context of allergy, asthma, respiratory infection and vaccination. Thus, the Randall lab is defining the cellular and molecular mechanisms behind these differences.
Funding
Dr. Randall receives his funding from the NIH and the NY Department of Health.
Publications
- Moyron-Quiroz, JE, J Rangel-Moreno, K Kusser, L. Hartson, F. Sprague, S. Goodrich, D.L. Woodland, FE Lund and T.D. Randall. 2004. Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat. Med. 10:927-934.
- Moyron-Quiroz, JE, J. Rangel-Moreno, L. Hartson, K Kusser, M.P. Tighe, KD Klonowski, L Lefrancois, LS Cauley, A.G. Harmsen, F.E. Lund and TD Randall. 2006. Persistence and responsiveness of immunologic memory in the absence of secondary lymphoid organs. Immunity. 25:643-654
- Rangel-Moreno J, L Hartson, C Navarro, M Gaxiola, M Selman and TD Randall 2006. Inducible Bronchus Associated Lymphoid Tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J. Clin. Invest. 116:3183-3194.
- Rangel-Moreno, J. J Moyron-Quiroz, L. Hartson, K Kusser and TD Randall. 2007. Pulmonary expression of CXCL13, CCL19 and CCL21 is essential for local immunity to influenza. Proc. Natl. Acad. Sci (USA) 104:10577-10582.
- Carragher, DM, DA Kaminski, A Moquin, L Hartson and TD Randall. 2008. A novel role for non-neutralizing antibodies against nucleoprotein in facilitating resistance to influenza. J. Immunol. 181:4168-4176.
