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Mitochondrial Reearch & Innovation Group

Member Profiles and Research Pages


MRIG Core Group

Sheu, Shey-Shing (Pharmacology and Physiology), Calcium signaling in normal and diseased hearts and neurons, and scientific coordiantion of MRIG.
*Visit our Lab Web Page.

Robotham, James L. (Anesthesiology), Role of mitochondria in regulating responses to acute stress and administrative coordination of MRIG.

Anders, M. W. (Pharmacology and Physiology), Mitochondrial glutathione homeostasis and the mitochondrial bioactivation of toxic chemicals, and administrative direction of program for mitochondrial-targeted drug development.
*Visit our Lab Web Page.

Brookes, Paul S. (Anesthesiology), Mitochondrial protein modifications mediated by reactive oxygen and nitrogen species, in the context of cardiac ischemic injury and protection.

Gunter, Thomas E. (Biochemistry and Biophysics), Mitochondria calcium transport and control of ox-phos: Mitochondrial roles in apoptosis and in manganese toxicity.

Johnson, Gail V.W. (Anesthesiology), Mitochondrial dysfunction and the molecular mechanisms of neurodegeneration; the regulation and function of transglutaminase 2; tau pathology in Alzheimer’s disease; the role of mitochondria in the pathogenesis of Huntington’s disease.

Yoon, Yisang (Anesthesiology), Regulation of mitochondrial dynamic morphology and form-function correlation in hyperglycemia, neurodegeneration, and cardiac function.

 

Faculty Profiles and Research Pages

Anders, M. W. (Pharmacology and Physiology), Mitochondrial glutathione homeostasis and the mitochondrial bioactivation of toxic chemicals, and administrative director of program for mitochondrial-targeted drug development.
*Visit our Lab Web Page.

Berk, Bradford C. (Medicine, Center for Cardiovascular Research), Molecular biology and genetics of cardiovascular disease.

Brookes, Paul S. (Anesthesiology), Mitochondrial protein modifications mediated by reactive oxygen and nitrogen species, in the context of cardiac ischemic injury and protection.

Coleman, Paul D. (Neurobiology and Anatomy), Neurobiology of aging and Alzheimer's Disease.

Dirksen, Robert T. (Pharmacology and Physiology), Calcium channel structure and function.

Eliseev, Roman A. (Center for Musculoskeletal Research, Wilmot Cancer Center), Role of mitochondria in apoptosis; anti- and pro-apoptotic mechanisms in cancer.

Freeman, Robert S. (Pharmacology and Physiology), Molecular mechanisms of neuronal apoptosis and the signal transduction pathways utilized by neurotrophic factors to promote cell survival. *Visit our Lab Web Page.

Gross, Robert A. (Neurology), Research focuses on the role of mitochondria in excitotoxic neuronal injury.

Gunter, Thomas E. (Biochemistry and Biophysics), Mitochondria calcium transport and control of ox-phos: Mitochondrial roles in apoptosis and in manganese toxicity.

Johnson, Gail V.W. (Anesthesiology), Mitochondrial dysfunction and the molecular mechanisms of neurodegeneration; the regulation and function of transglutaminase 2; tau pathology in Alzheimer’s disease; the role of mitochondria in the pathogenesis of Huntington’s disease.

Noble, Mark (Center for Cancer Biology), Stem cell biology, regeneration in the central nervous system, redox modulation of precursor cell function, developmental disorders, brain tumor biology and adverse effects of chemotherapy of neural stem cell populations.

Pearce, David A. (Center for Aging and Developmental Biology), Mitochondrial protein turnover. *Visit our Lab Web Page.

Rahman, Irfan (Environmental Medicine), Oxidant and cigarette smoke-mediated glutathione regulation, lung inflammation and COPD.

Robotham, James L. (Anesthesiology), Role of mitochondria in regulating responses to acute stress and administrative coordination of MRIG.

Sherman, Fred (Biochemistry and Biophysics), Yeast molecular biology and genetics; gene expression; cytochrome c biosynthesis and degradation.

Sheu, Shey-Shing (Pharmacology and Physiology), Calcium signaling in normal and diseased hearts and neurons, and scientific coordination of MRIG. *Visit our Lab Web Page.

Sia, Elaine A. (Biology), Mutagenesis and repair of the mitochondrial genome of Saccharomyces cerevisiae.

Sims, Peter J. (Pathology and Laboratory Medicine), The biological function of phospholipid scramblases (PLSCRs).

Tieu, Kim (Environmental Medicine, Center for Aging and Developmental Biology), Mechanisms of neurodegeneration and neuroprotection.

White, Jim R. (Pulmonary and Critical Care Medicine), Role of mitochondria in hypoxic pulmonary vasoconstriction.

Wiedmer, Therese (Pathology and Laboratory Medicine), Role of phospholipid scramblases (PLSCRs) in cell response to growth factors.

Yoon, Yisang (Anesthesiology), Regulation of mitochondrial dynamic morphology and form-function correlation in hyperglycemia, neurodegeneration, and cardiac function.

Yule, David I. (Pharmacology and Physiology), Mechanisms underlying Ca2+ signaling events in exocrine cells. *Visit our Lab Web Page.