| Goals of the MRIG |
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| 1. |
Address the need for high-quality, integrated basic-science and clinical research to elucidate the roles of mitochondrial function in human health and to redefine mitochondrial disease in its broader context. |
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| 2. |
Discover and define fundamental mechanisms of mitochondrial activities necessary for basal cell and organ function and in response to acute or chronic stress states of multiple origins to expand grant support for our basic and translational research. |
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| 3. |
Utilize our understanding of mitochondrial mechanisms to develop mitochondrial-targeted therapeutic strategies for a range of disease states through design, synthesis, and testing of novel molecules focusing initially on development and delivery of antioxidant species that will enhance mitochondrial function. |
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Expand the range and productivity of our basic-science studies by focused effective collaborations with, and recruitment of, molecular, cell, and systems oriented biologists, toxicologists and medicinal chemists. |
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Optimize the value of our intellectual property that flows from our scientific and drug-development program with experienced pharmaceutical industry consultation to identify process and opportunities to identify funding sources to support expansion of the MRIG goals. |
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Develop intramural and extramural clinical research capacity to facilitate Phase 1 drug development testing, later expanding to Phase 2 studies. |
The University of Rochester is
an Equal Opportunity/Affirmative Action Employer. Applications from
qualified women and underrepresented minorities are encouraged.
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